Synergistic assembly of human pre-spliceosomes across introns and exons
Most human genes contain multiple introns, necessitating mechanisms to effectively define exons and ensure their proper connection by spliceosomes. Human spliceosome assembly involves both cross-intron and cross-exon interactions, but how these work together is unclear. We examined in human nuclear...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/37751 |