COVID-19 and the Nervous System from a Cuban Experience
Neuropsychiatric manifestations of viral infections (both per se and secondary to the neuroinflammatory reaction of the host) are mainly attributed to immunological reactions, so many aspects of their pathogenesis are still nuclear. Some novel therapeutic strategies are progressively emerging in whi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-09-01
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| Series: | Behavioral Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-328X/13/9/776 |
| _version_ | 1797581241423233024 |
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| author | Maria de los Angeles Robinson-Agramonte Teresa Serrano Sánchez Elena Noris García Orlando Rafael Serrano Barrera Dario Siniscalco |
| author_facet | Maria de los Angeles Robinson-Agramonte Teresa Serrano Sánchez Elena Noris García Orlando Rafael Serrano Barrera Dario Siniscalco |
| author_sort | Maria de los Angeles Robinson-Agramonte |
| collection | DOAJ |
| description | Neuropsychiatric manifestations of viral infections (both per se and secondary to the neuroinflammatory reaction of the host) are mainly attributed to immunological reactions, so many aspects of their pathogenesis are still nuclear. Some novel therapeutic strategies are progressively emerging in which a vaccination may be having a particular impact on recovery and reduction of death. In this context, it is accepted that the SARS-CoV-2 virus is profoundly neurotropic and neuroinvasive, with various effects on the nervous system, although there is no complete understanding of the mechanism of neuroinvasion, brain injury, or short- or long-term neuropsychiatric sequelae. Therefore, it is necessary to understand the post-infectious manifestations of COVID-19 to guide the management of neuropsychiatric diseases. Thus, based on different research groups focused on this field, in this manuscript we summarize papers on COVID-19 and the nervous system (NS) published in a series of articles by Cuban authors. This review focuses on cognitive and affective emotional states, pathogenesis, biomarkers, clinical manifestations, and intervention strategies. |
| first_indexed | 2024-03-10T23:02:35Z |
| format | Article |
| id | doaj.art-87a8d53bb4524a6c86119a2d9af2cbd9 |
| institution | Directory Open Access Journal |
| issn | 2076-328X |
| language | English |
| last_indexed | 2024-03-10T23:02:35Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Behavioral Sciences |
| spelling | doaj.art-87a8d53bb4524a6c86119a2d9af2cbd92023-11-19T09:35:37ZengMDPI AGBehavioral Sciences2076-328X2023-09-0113977610.3390/bs13090776COVID-19 and the Nervous System from a Cuban ExperienceMaria de los Angeles Robinson-Agramonte0Teresa Serrano Sánchez1Elena Noris García2Orlando Rafael Serrano Barrera3Dario Siniscalco4International Center for Neurological Restoration, Neuroimmunology Department, University of Medical Sciences of Havana, Havana 11300, CubaInternational Center for Neurological Restoration, Neuroimmunology Department, University of Medical Sciences of Havana, Havana 11300, CubaInstitute of Nephrology, Department of Immunology, Havana 10600, Cuba“Dr. Ernesto Guevara de la Serna” General Hospital, Las Tunas University of Medical Sciences, Las Tunas 75100, CubaDepartment of Experimental Medicine, Division of Molecular Biology, Biotechnology and Histology, University of Campania, 80138 Naples, ItalyNeuropsychiatric manifestations of viral infections (both per se and secondary to the neuroinflammatory reaction of the host) are mainly attributed to immunological reactions, so many aspects of their pathogenesis are still nuclear. Some novel therapeutic strategies are progressively emerging in which a vaccination may be having a particular impact on recovery and reduction of death. In this context, it is accepted that the SARS-CoV-2 virus is profoundly neurotropic and neuroinvasive, with various effects on the nervous system, although there is no complete understanding of the mechanism of neuroinvasion, brain injury, or short- or long-term neuropsychiatric sequelae. Therefore, it is necessary to understand the post-infectious manifestations of COVID-19 to guide the management of neuropsychiatric diseases. Thus, based on different research groups focused on this field, in this manuscript we summarize papers on COVID-19 and the nervous system (NS) published in a series of articles by Cuban authors. This review focuses on cognitive and affective emotional states, pathogenesis, biomarkers, clinical manifestations, and intervention strategies.https://www.mdpi.com/2076-328X/13/9/776COVID-19nervous systemneuroinflammationSARS-CoV-2neuropsychiatric disorderspsychoneuroimmunology |
| spellingShingle | Maria de los Angeles Robinson-Agramonte Teresa Serrano Sánchez Elena Noris García Orlando Rafael Serrano Barrera Dario Siniscalco COVID-19 and the Nervous System from a Cuban Experience Behavioral Sciences COVID-19 nervous system neuroinflammation SARS-CoV-2 neuropsychiatric disorders psychoneuroimmunology |
| title | COVID-19 and the Nervous System from a Cuban Experience |
| title_full | COVID-19 and the Nervous System from a Cuban Experience |
| title_fullStr | COVID-19 and the Nervous System from a Cuban Experience |
| title_full_unstemmed | COVID-19 and the Nervous System from a Cuban Experience |
| title_short | COVID-19 and the Nervous System from a Cuban Experience |
| title_sort | covid 19 and the nervous system from a cuban experience |
| topic | COVID-19 nervous system neuroinflammation SARS-CoV-2 neuropsychiatric disorders psychoneuroimmunology |
| url | https://www.mdpi.com/2076-328X/13/9/776 |
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