Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07)

Study protocol: mycophenolate mofetil as maintenance therapy after rituximab treatment for childhood-onset, complicated, frequently-relapsing nephrotic syndrome or steroid-dependent nephrotic syndrome: a multicenter double-blind, randomized, placebo-controlled trial (JSKDC07)

Abstract Background Idiopathic nephrotic syndrome (INS) is the most common chronic glomerular disease in children. Approximately 80–90% of patients with childhood INS have steroid-sensitive nephrotic syndrome (SSNS), and can obtain remission with steroid therapy, while the remainder have steroid-res...

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Bibliographic Details
Main Authors: Tomoko Horinouchi, Mayumi Sako, Koichi Nakanishi, Kenji Ishikura, Shuichi Ito, Hidefumi Nakamura, Mari Saito Oba, Kandai Nozu, Kazumoto Iijima
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Nephrology
Subjects:
Mycophenolate mofetil
rituximab.
frequently-relapsing nephrotic syndrome.
steroid-dependent nephrotic syndrome.
steroid-sensitive nephrotic syndrome.
multicenter, double-blind, randomized, placebo-controlled trial.
Online Access:http://link.springer.com/article/10.1186/s12882-018-1099-7

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