A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch
Abstract Objective This report documents a rare case of vulvar discharge associated with exogenous oestrogen exposure in a large‐breed dog. Case description A 4‐year‐old spayed Weimaraner bitch was presented for evaluation of inappetence and intermittent sanguineous vulvar discharge. Physical examin...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-09-01
|
| Series: | Veterinary Medicine and Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/vms3.860 |
| _version_ | 1818032376927748096 |
|---|---|
| author | Francesca Ivaldi Camille Ogdon Firdous A. Khan |
| author_facet | Francesca Ivaldi Camille Ogdon Firdous A. Khan |
| author_sort | Francesca Ivaldi |
| collection | DOAJ |
| description | Abstract Objective This report documents a rare case of vulvar discharge associated with exogenous oestrogen exposure in a large‐breed dog. Case description A 4‐year‐old spayed Weimaraner bitch was presented for evaluation of inappetence and intermittent sanguineous vulvar discharge. Physical examination, vaginal cytology, haematological, and ultrasonographic findings were indicative of a uterine stump pyometra. A celiotomy was performed, and the uterine stump appeared grossly cystic and thickened. Histopathological evaluation of the removed uterine stump and ovarian pedicles revealed cystic endometrial hyperplasia and no ovarian tissue. Fifteen days after surgery, the patient presented again with a sanguineous vulvar discharge. Vaginal cytology revealed predominantly superficial cells, indicating oestrogen influence. Further questioning of the owner revealed the long‐term use of a topical oestrogen cream by a member of the household. Serial examinations were performed, and the cytology remained uniform, with predominantly superficial cells, indicating continued oestrogen influence. Progesterone and anti‐Müllerian hormone tests were negative, which made the presence of ectopic ovarian tissue unlikely. These results coupled with the history of topical oestrogen cream use in the household suggested that the patient's clinical signs were most likely due to exogenous oestrogen exposure. After the owner implemented various recommendations made to prevent the exposure, the clinical signs resolved completely. Conclusions This case demonstrates that although rare, exogenous oestrogen exposure can be a cause of vulvar discharge in a large‐breed spayed bitch. Therefore, regardless of the breed, exogenous oestrogen exposure must be included in the list of differential diagnoses for all clinical presentations associated with oestrogenic influence in dogs. |
| first_indexed | 2024-12-10T06:06:24Z |
| format | Article |
| id | doaj.art-87af104f6cca492a8234e655a3a52a08 |
| institution | Directory Open Access Journal |
| issn | 2053-1095 |
| language | English |
| last_indexed | 2024-12-10T06:06:24Z |
| publishDate | 2022-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine and Science |
| spelling | doaj.art-87af104f6cca492a8234e655a3a52a082022-12-22T01:59:41ZengWileyVeterinary Medicine and Science2053-10952022-09-01851872187610.1002/vms3.860A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitchFrancesca Ivaldi0Camille Ogdon1Firdous A. Khan2Department of Small Animal Medicine and Surgery School of Veterinary Medicine St. George's University True Blue GrenadaSchool of Veterinary Medicine St. George's University True Blue GrenadaDepartment of Large Animal Medicine and Surgery School of Veterinary Medicine St. George's University True Blue GrenadaAbstract Objective This report documents a rare case of vulvar discharge associated with exogenous oestrogen exposure in a large‐breed dog. Case description A 4‐year‐old spayed Weimaraner bitch was presented for evaluation of inappetence and intermittent sanguineous vulvar discharge. Physical examination, vaginal cytology, haematological, and ultrasonographic findings were indicative of a uterine stump pyometra. A celiotomy was performed, and the uterine stump appeared grossly cystic and thickened. Histopathological evaluation of the removed uterine stump and ovarian pedicles revealed cystic endometrial hyperplasia and no ovarian tissue. Fifteen days after surgery, the patient presented again with a sanguineous vulvar discharge. Vaginal cytology revealed predominantly superficial cells, indicating oestrogen influence. Further questioning of the owner revealed the long‐term use of a topical oestrogen cream by a member of the household. Serial examinations were performed, and the cytology remained uniform, with predominantly superficial cells, indicating continued oestrogen influence. Progesterone and anti‐Müllerian hormone tests were negative, which made the presence of ectopic ovarian tissue unlikely. These results coupled with the history of topical oestrogen cream use in the household suggested that the patient's clinical signs were most likely due to exogenous oestrogen exposure. After the owner implemented various recommendations made to prevent the exposure, the clinical signs resolved completely. Conclusions This case demonstrates that although rare, exogenous oestrogen exposure can be a cause of vulvar discharge in a large‐breed spayed bitch. Therefore, regardless of the breed, exogenous oestrogen exposure must be included in the list of differential diagnoses for all clinical presentations associated with oestrogenic influence in dogs.https://doi.org/10.1002/vms3.860caninecase reportcystic endometrial hyperplasiaoestrogenvulvar discharge |
| spellingShingle | Francesca Ivaldi Camille Ogdon Firdous A. Khan A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch Veterinary Medicine and Science canine case report cystic endometrial hyperplasia oestrogen vulvar discharge |
| title | A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch |
| title_full | A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch |
| title_fullStr | A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch |
| title_full_unstemmed | A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch |
| title_short | A rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed Weimaraner bitch |
| title_sort | rare case of vulvar discharge associated with exogenous oestrogen exposure in a spayed weimaraner bitch |
| topic | canine case report cystic endometrial hyperplasia oestrogen vulvar discharge |
| url | https://doi.org/10.1002/vms3.860 |
| work_keys_str_mv | AT francescaivaldi ararecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch AT camilleogdon ararecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch AT firdousakhan ararecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch AT francescaivaldi rarecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch AT camilleogdon rarecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch AT firdousakhan rarecaseofvulvardischargeassociatedwithexogenousoestrogenexposureinaspayedweimaranerbitch |