Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial

Background: In India, more than half of the pregnant women suffer from anemia. Low compliance to iron supplementation is one of the important reasons. Objectives: The objective of the study is to estimate the reduction in the prevalence of anemia, improvement in iron status, and to compare the compl...

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Main Authors: Farhad Ahamed, Kapil Yadav, Shashi Kant, Renu Saxena, Mohan Bairwa, Chandrakant S Pandav
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Indian Journal of Public Health
Subjects:
Online Access:http://www.ijph.in/article.asp?issn=0019-557X;year=2018;volume=62;issue=4;spage=287;epage=293;aulast=Ahamed
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author Farhad Ahamed
Kapil Yadav
Shashi Kant
Renu Saxena
Mohan Bairwa
Chandrakant S Pandav
author_facet Farhad Ahamed
Kapil Yadav
Shashi Kant
Renu Saxena
Mohan Bairwa
Chandrakant S Pandav
author_sort Farhad Ahamed
collection DOAJ
description Background: In India, more than half of the pregnant women suffer from anemia. Low compliance to iron supplementation is one of the important reasons. Objectives: The objective of the study is to estimate the reduction in the prevalence of anemia, improvement in iron status, and to compare the compliance to oral iron supplementation during pregnancy between directly observed iron-folic acid (IFA) supplementation group and control group. Methods: This was a community-based open labeled parallel block-randomized controlled trial including 400 pregnant women in a rural setting of north India. In the intervention group, the first dose of IFA every week was supervised by ASHA and women were instructed to take the remaining tablets during the week as per the prescription. In control group, IFA tablets were supplemented without direct supervision. Results: After 100 days of IFA supplementation, the reduction in anemia in the intervention group was 6% higher as compared to control group (P = 0.219). The increase in the mean hemoglobin level over and above control group was 0.52 g/dl in intervention group (P < 0.001). However, the mean increase in serum ferritin level in the intervention group was similar to the control group. The mean percentage compliance in the intervention group was almost 9% higher than that of control group (P = 0.001). Conclusion: Directly supervised oral iron (IFA) supplementation improves compliance to oral iron (IFA) supplementation and also improves hemoglobin status among pregnant women. However, the mean increase in serum ferritin and reduction in the prevalence of anemia in the intervention group were not higher than the control group.
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spelling doaj.art-87b3c34db3c64ce490723584ec3f6a8b2022-12-22T03:46:02ZengWolters Kluwer Medknow PublicationsIndian Journal of Public Health0019-557X2018-01-0162428729310.4103/ijph.IJPH_313_17Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trialFarhad AhamedKapil YadavShashi KantRenu SaxenaMohan BairwaChandrakant S PandavBackground: In India, more than half of the pregnant women suffer from anemia. Low compliance to iron supplementation is one of the important reasons. Objectives: The objective of the study is to estimate the reduction in the prevalence of anemia, improvement in iron status, and to compare the compliance to oral iron supplementation during pregnancy between directly observed iron-folic acid (IFA) supplementation group and control group. Methods: This was a community-based open labeled parallel block-randomized controlled trial including 400 pregnant women in a rural setting of north India. In the intervention group, the first dose of IFA every week was supervised by ASHA and women were instructed to take the remaining tablets during the week as per the prescription. In control group, IFA tablets were supplemented without direct supervision. Results: After 100 days of IFA supplementation, the reduction in anemia in the intervention group was 6% higher as compared to control group (P = 0.219). The increase in the mean hemoglobin level over and above control group was 0.52 g/dl in intervention group (P < 0.001). However, the mean increase in serum ferritin level in the intervention group was similar to the control group. The mean percentage compliance in the intervention group was almost 9% higher than that of control group (P = 0.001). Conclusion: Directly supervised oral iron (IFA) supplementation improves compliance to oral iron (IFA) supplementation and also improves hemoglobin status among pregnant women. However, the mean increase in serum ferritin and reduction in the prevalence of anemia in the intervention group were not higher than the control group.http://www.ijph.in/article.asp?issn=0019-557X;year=2018;volume=62;issue=4;spage=287;epage=293;aulast=AhamedAnemia prevalencecompliancedirectly observediron-folic acidoral iron supplementationpregnant women
spellingShingle Farhad Ahamed
Kapil Yadav
Shashi Kant
Renu Saxena
Mohan Bairwa
Chandrakant S Pandav
Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
Indian Journal of Public Health
Anemia prevalence
compliance
directly observed
iron-folic acid
oral iron supplementation
pregnant women
title Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
title_full Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
title_fullStr Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
title_full_unstemmed Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
title_short Effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in Haryana: A randomized controlled trial
title_sort effect of directly observed oral iron supplementation during pregnancy on iron status in a rural population in haryana a randomized controlled trial
topic Anemia prevalence
compliance
directly observed
iron-folic acid
oral iron supplementation
pregnant women
url http://www.ijph.in/article.asp?issn=0019-557X;year=2018;volume=62;issue=4;spage=287;epage=293;aulast=Ahamed
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