A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous
Abstract This case report discusses the rare coexistence of Systemic Lupus Erythematosus (SLE) and Rheumatic Heart Disease (RHD) in a 46‐year‐old female patient, challenging the conventional understanding of their distinct presentations. The patient exhibited migratory joint pains, palpitations, and...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.8430 |
| _version_ | 1827365513957736448 |
|---|---|
| author | Sanjay Dhungana Abhishek Pandey Nijita Aryal Kshitiz Kayastha Santosh Pandey Mukunda Thakur |
| author_facet | Sanjay Dhungana Abhishek Pandey Nijita Aryal Kshitiz Kayastha Santosh Pandey Mukunda Thakur |
| author_sort | Sanjay Dhungana |
| collection | DOAJ |
| description | Abstract This case report discusses the rare coexistence of Systemic Lupus Erythematosus (SLE) and Rheumatic Heart Disease (RHD) in a 46‐year‐old female patient, challenging the conventional understanding of their distinct presentations. The patient exhibited migratory joint pains, palpitations, and shortness of breath. Diagnostic investigations confirmed SLE based on EULAR/ACR criteria, with positive anti‐nuclear and anti‐dsDNA antibodies. Concurrently, transthoracic echocardiography revealed severe mitral stenosis and regurgitation, leading to the diagnosis of RHD. The patient underwent successful open‐heart surgery with mitral valve replacement. The discussion explores the rarity of this coexistence, emphasizing the need for cautious consideration and further research into potential immunological overlaps between SLE and RHD. The report concludes with a call for comprehensive studies to enhance our understanding of the pathophysiology connecting these two conditions. |
| first_indexed | 2024-03-08T08:29:35Z |
| format | Article |
| id | doaj.art-87b3f685700c45f1b5c9849ba69efdab |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-08T08:29:35Z |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-87b3f685700c45f1b5c9849ba69efdab2024-02-02T03:36:32ZengWileyClinical Case Reports2050-09042024-01-01121n/an/a10.1002/ccr3.8430A rare case report of coexisting rheumatic heart disease and systemic lupus erythematousSanjay Dhungana0Abhishek Pandey1Nijita Aryal2Kshitiz Kayastha3Santosh Pandey4Mukunda Thakur5Nepal Medical College Teaching Hospital Kathmandu NepalNepal Medical College Teaching Hospital Kathmandu NepalNepal Medical College Teaching Hospital Kathmandu NepalNepal Medical College Teaching Hospital Kathmandu NepalNepal Medical College Teaching Hospital Kathmandu NepalNepal Medical College Teaching Hospital Kathmandu NepalAbstract This case report discusses the rare coexistence of Systemic Lupus Erythematosus (SLE) and Rheumatic Heart Disease (RHD) in a 46‐year‐old female patient, challenging the conventional understanding of their distinct presentations. The patient exhibited migratory joint pains, palpitations, and shortness of breath. Diagnostic investigations confirmed SLE based on EULAR/ACR criteria, with positive anti‐nuclear and anti‐dsDNA antibodies. Concurrently, transthoracic echocardiography revealed severe mitral stenosis and regurgitation, leading to the diagnosis of RHD. The patient underwent successful open‐heart surgery with mitral valve replacement. The discussion explores the rarity of this coexistence, emphasizing the need for cautious consideration and further research into potential immunological overlaps between SLE and RHD. The report concludes with a call for comprehensive studies to enhance our understanding of the pathophysiology connecting these two conditions.https://doi.org/10.1002/ccr3.8430coexistancerheumatic heart diseasesystemic lupus erythematosus |
| spellingShingle | Sanjay Dhungana Abhishek Pandey Nijita Aryal Kshitiz Kayastha Santosh Pandey Mukunda Thakur A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous Clinical Case Reports coexistance rheumatic heart disease systemic lupus erythematosus |
| title | A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| title_full | A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| title_fullStr | A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| title_full_unstemmed | A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| title_short | A rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| title_sort | rare case report of coexisting rheumatic heart disease and systemic lupus erythematous |
| topic | coexistance rheumatic heart disease systemic lupus erythematosus |
| url | https://doi.org/10.1002/ccr3.8430 |
| work_keys_str_mv | AT sanjaydhungana ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT abhishekpandey ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT nijitaaryal ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT kshitizkayastha ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT santoshpandey ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT mukundathakur ararecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT sanjaydhungana rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT abhishekpandey rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT nijitaaryal rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT kshitizkayastha rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT santoshpandey rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous AT mukundathakur rarecasereportofcoexistingrheumaticheartdiseaseandsystemiclupuserythematous |