Thermostable DNA ligases from hyperthermophiles in biotechnology

Thermostable DNA ligases from hyperthermophiles in biotechnology

DNA ligase is an important enzyme ubiquitous in all three kingdoms of life that can ligate DNA strands, thus playing essential roles in DNA replication, repair and recombination in vivo. In vitro, DNA ligase is also used in biotechnological applications requiring in DNA manipulation, including molec...

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Bibliographic Details
Main Authors: Jingru Shi, Philippe M. Oger, Peng Cao, Likui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Microbiology
Subjects:
DNA ligase
ligase cycling reaction
DNA manipulation
thermostability
hyperthermophiles
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1198784/full

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