Synthesis of New Methoxy Actived Mono and Bis-indole Compounds

An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate. The reaction of this compound with acetone yielded indole based imine compound. The structure of targeted compound was...

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Main Author: Hakan Kandemir
Format: Article
Language:English
Published: Hitit University 2022-09-01
Series:Hittite Journal of Science and Engineering
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/2591114
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author Hakan Kandemir
author_facet Hakan Kandemir
author_sort Hakan Kandemir
collection DOAJ
description An indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate. The reaction of this compound with acetone yielded indole based imine compound. The structure of targeted compound was identified by mass and 1H spectroscopy along with single crystal X-ray diffraction technique. Also, bromination of bis-indole with N-bromo succinimide was produced corresponding bromo bis-indol derivative.
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spelling doaj.art-87b73bdd30ae45888c1696485b16b8432023-10-10T11:17:28ZengHitit UniversityHittite Journal of Science and Engineering2148-41712022-09-019323523910.17350/HJSE19030000276150Synthesis of New Methoxy Actived Mono and Bis-indole CompoundsHakan Kandemir0TEKIRDAG NAMIK KEMAL UNIVERSITYAn indole hydrazone has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole-7-carbaldehyde with hydrazine hydrate. The reaction of this compound with acetone yielded indole based imine compound. The structure of targeted compound was identified by mass and 1H spectroscopy along with single crystal X-ray diffraction technique. Also, bromination of bis-indole with N-bromo succinimide was produced corresponding bromo bis-indol derivative.https://dergipark.org.tr/tr/download/article-file/2591114indolebis-indolehydrazonebromination
spellingShingle Hakan Kandemir
Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
Hittite Journal of Science and Engineering
indole
bis-indole
hydrazone
bromination
title Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
title_full Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
title_fullStr Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
title_full_unstemmed Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
title_short Synthesis of New Methoxy Actived Mono and Bis-indole Compounds
title_sort synthesis of new methoxy actived mono and bis indole compounds
topic indole
bis-indole
hydrazone
bromination
url https://dergipark.org.tr/tr/download/article-file/2591114
work_keys_str_mv AT hakankandemir synthesisofnewmethoxyactivedmonoandbisindolecompounds