Non-Oncological Radiotherapy: A Review of Modern Approaches

Despite being usually delivered in oncological patients, radiotherapy can be used as a successful treatment for several non-malignant disorders. Even though this use of radiotherapy has been scarcely investigated since the 1950s, more recent interest has actually shed the light on this approach. Thu...

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Main Authors: Valerio Nardone, Emma D’Ippolito, Roberta Grassi, Angelo Sangiovanni, Federico Gagliardi, Giuseppina De Marco, Vittorio Salvatore Menditti, Luca D’Ambrosio, Fabrizio Cioce, Luca Boldrini, Viola Salvestrini, Carlo Greco, Isacco Desideri, Francesca De Felice, Ida D’Onofrio, Roberto Grassi, Alfonso Reginelli, Salvatore Cappabianca
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/12/10/1677
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author Valerio Nardone
Emma D’Ippolito
Roberta Grassi
Angelo Sangiovanni
Federico Gagliardi
Giuseppina De Marco
Vittorio Salvatore Menditti
Luca D’Ambrosio
Fabrizio Cioce
Luca Boldrini
Viola Salvestrini
Carlo Greco
Isacco Desideri
Francesca De Felice
Ida D’Onofrio
Roberto Grassi
Alfonso Reginelli
Salvatore Cappabianca
author_facet Valerio Nardone
Emma D’Ippolito
Roberta Grassi
Angelo Sangiovanni
Federico Gagliardi
Giuseppina De Marco
Vittorio Salvatore Menditti
Luca D’Ambrosio
Fabrizio Cioce
Luca Boldrini
Viola Salvestrini
Carlo Greco
Isacco Desideri
Francesca De Felice
Ida D’Onofrio
Roberto Grassi
Alfonso Reginelli
Salvatore Cappabianca
author_sort Valerio Nardone
collection DOAJ
description Despite being usually delivered in oncological patients, radiotherapy can be used as a successful treatment for several non-malignant disorders. Even though this use of radiotherapy has been scarcely investigated since the 1950s, more recent interest has actually shed the light on this approach. Thus, the aim of this narrative review is to analyze the applications of non-oncological radiotherapy in different disorders. Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used. This review contains a narrative report and a critical discussion of non-oncological radiotherapy approaches. In conclusion, non-oncological radiotherapy is a safe and efficacious approach to treat several disorders that needs to be further investigated and used in clinical practice.
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spelling doaj.art-87ba15f1770f49fd8e93dd9076b8747b2023-11-24T00:50:13ZengMDPI AGJournal of Personalized Medicine2075-44262022-10-011210167710.3390/jpm12101677Non-Oncological Radiotherapy: A Review of Modern ApproachesValerio Nardone0Emma D’Ippolito1Roberta Grassi2Angelo Sangiovanni3Federico Gagliardi4Giuseppina De Marco5Vittorio Salvatore Menditti6Luca D’Ambrosio7Fabrizio Cioce8Luca Boldrini9Viola Salvestrini10Carlo Greco11Isacco Desideri12Francesca De Felice13Ida D’Onofrio14Roberto Grassi15Alfonso Reginelli16Salvatore Cappabianca17Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyRadiation Oncology, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Largo Agostino Gemelli, 00168 Rome, ItalyRadiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Department of Experimental and Clinical Biomedical Sciences, University of Florence, 50134 Florence, ItalyDepartment of Radiation Oncology, Università Campus Bio-Medico di Roma, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 00128 Rome, ItalyRadiation Oncology, Azienda Ospedaliero-Universitaria Careggi, Department of Experimental and Clinical Biomedical Sciences, University of Florence, 50134 Florence, ItalyRadiation Oncology, Policlinico Umberto I “Sapienza” University of Rome, Viale Regina Elena 326, 00161 Rome, ItalyRadiation Oncology, Ospedale del Mare, ASL Napoli 1 Centro, 80147 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDepartment of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Naples, ItalyDespite being usually delivered in oncological patients, radiotherapy can be used as a successful treatment for several non-malignant disorders. Even though this use of radiotherapy has been scarcely investigated since the 1950s, more recent interest has actually shed the light on this approach. Thus, the aim of this narrative review is to analyze the applications of non-oncological radiotherapy in different disorders. Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used. This review contains a narrative report and a critical discussion of non-oncological radiotherapy approaches. In conclusion, non-oncological radiotherapy is a safe and efficacious approach to treat several disorders that needs to be further investigated and used in clinical practice.https://www.mdpi.com/2075-4426/12/10/1677radiotherapynon-malignant disordersnon-oncological radiotherapy
spellingShingle Valerio Nardone
Emma D’Ippolito
Roberta Grassi
Angelo Sangiovanni
Federico Gagliardi
Giuseppina De Marco
Vittorio Salvatore Menditti
Luca D’Ambrosio
Fabrizio Cioce
Luca Boldrini
Viola Salvestrini
Carlo Greco
Isacco Desideri
Francesca De Felice
Ida D’Onofrio
Roberto Grassi
Alfonso Reginelli
Salvatore Cappabianca
Non-Oncological Radiotherapy: A Review of Modern Approaches
Journal of Personalized Medicine
radiotherapy
non-malignant disorders
non-oncological radiotherapy
title Non-Oncological Radiotherapy: A Review of Modern Approaches
title_full Non-Oncological Radiotherapy: A Review of Modern Approaches
title_fullStr Non-Oncological Radiotherapy: A Review of Modern Approaches
title_full_unstemmed Non-Oncological Radiotherapy: A Review of Modern Approaches
title_short Non-Oncological Radiotherapy: A Review of Modern Approaches
title_sort non oncological radiotherapy a review of modern approaches
topic radiotherapy
non-malignant disorders
non-oncological radiotherapy
url https://www.mdpi.com/2075-4426/12/10/1677
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