Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

In the hypothalamus, the arcuate nucleus (ARC) contains AgRP-neurons that regulate energy balance as well as GHRH-neurons that regulate linear growth. Here, the authors looked at how the transcription factors Dlx1/2 and Otp link development of AgRP- and GHRH-neurons.

Bibliographic Details
Main Authors: Bora Lee, Janghyun Kim, Taekyeong An, Sangsoo Kim, Esha M. Patel, Jacob Raber, Soo-Kyung Lee, Seunghee Lee, Jae W. Lee
Format: Article
Language:English
Published: Nature Portfolio 2018-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-04377-4

Internet

https://doi.org/10.1038/s41467-018-04377-4

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