SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation

SIRT7 orchestrates melanoma progression by simultaneously promoting cell survival and immune evasion via UPR activation

Abstract Melanoma is the most lethal type of skin cancer, originating from the malignant transformation of melanocyte. While the development of targeted therapy and immunotherapy has gained revolutionary advances in potentiating the therapeutic effect, the prognosis of patients with melanoma is stil...

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Bibliographic Details
Main Authors: Xiuli Yi, Huina Wang, Yuqi Yang, Hao Wang, Hengxiang Zhang, Sen Guo, Jianru Chen, Juan Du, Yangzi Tian, Jingjing Ma, Baolu Zhang, Lili Wu, Qiong Shi, Tianwen Gao, Weinan Guo, Chunying Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01314-w

Internet

https://doi.org/10.1038/s41392-023-01314-w

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