Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury

Histone methyltransferase KMT2D contributes to the protection of myocardial ischemic injury

Histone H3 lysine 4 (H3K4) methyltransferase 2D (KMT2D) plays an important role in cell development in early life. However, the function of KMT2D in adult cells such as cardiomyocytes or neurons has not been reported. In this study, cardiomyocyte-specific KMT2D knockout (KMT2D-cKO) and control (KMT2...

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Bibliographic Details
Main Authors:	Shu-Bao Liu, Xiang-Min Meng, Yu-Meng Li, Jun-Meng Wang, Hui-Hui Guo, Chaochen Wang, Bing-Mei Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-07-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	methyltransferase serum transcriptional regulation glucocorticoid response element ischemia
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2022.946484/full

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