The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue
The monoglyceride pathway for the synthesis of triglycerides has been investigated employing subcellular fractions and whole cell preparations of white and brown adipose tissue. Conclusive evidence has been obtained for the monoglyceride pathway in these tissues by employing the 2-monoether analogue...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
1971-03-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520395213 |
| _version_ | 1818671933879746560 |
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| author | F. MICHAEL SCHULTZ JOHN M. JOHNSTON |
| author_facet | F. MICHAEL SCHULTZ JOHN M. JOHNSTON |
| author_sort | F. MICHAEL SCHULTZ |
| collection | DOAJ |
| description | The monoglyceride pathway for the synthesis of triglycerides has been investigated employing subcellular fractions and whole cell preparations of white and brown adipose tissue. Conclusive evidence has been obtained for the monoglyceride pathway in these tissues by employing the 2-monoether analogue of 2-monoolein as the substrate. The monoglyceride and α-glycerophosphate pathways were primarily found in the microsomal fraction. In these in vitro systems the activity of the monoglyceride pathway compared with the α-glycerophosphate pathway was of the same order of magnitude in whole cell preparations and was approximately one-half the activity of the α-glycerophosphate pathway when the microsomal fraction was employed. |
| first_indexed | 2024-12-17T07:31:53Z |
| format | Article |
| id | doaj.art-87ce418009cd4f4aa0bf545f3c55c907 |
| institution | Directory Open Access Journal |
| issn | 0022-2275 |
| language | English |
| last_indexed | 2024-12-17T07:31:53Z |
| publishDate | 1971-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Lipid Research |
| spelling | doaj.art-87ce418009cd4f4aa0bf545f3c55c9072022-12-21T21:58:28ZengElsevierJournal of Lipid Research0022-22751971-03-01122132138The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissueF. MICHAEL SCHULTZ0JOHN M. JOHNSTON1Department of Biochemistry, The University of Texas (Southwestern) Medical School, Dallas, Texas 75235Department of Biochemistry, The University of Texas (Southwestern) Medical School, Dallas, Texas 75235The monoglyceride pathway for the synthesis of triglycerides has been investigated employing subcellular fractions and whole cell preparations of white and brown adipose tissue. Conclusive evidence has been obtained for the monoglyceride pathway in these tissues by employing the 2-monoether analogue of 2-monoolein as the substrate. The monoglyceride and α-glycerophosphate pathways were primarily found in the microsomal fraction. In these in vitro systems the activity of the monoglyceride pathway compared with the α-glycerophosphate pathway was of the same order of magnitude in whole cell preparations and was approximately one-half the activity of the α-glycerophosphate pathway when the microsomal fraction was employed.http://www.sciencedirect.com/science/article/pii/S0022227520395213subcellular locationbrown and white adipose tissue |
| spellingShingle | F. MICHAEL SCHULTZ JOHN M. JOHNSTON The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue Journal of Lipid Research subcellular location brown and white adipose tissue |
| title | The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| title_full | The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| title_fullStr | The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| title_full_unstemmed | The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| title_short | The synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| title_sort | synthesis of higher glycerides via the monoglyceride pathway in hamster adipose tissue |
| topic | subcellular location brown and white adipose tissue |
| url | http://www.sciencedirect.com/science/article/pii/S0022227520395213 |
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