Chemoresistance of PRAME-expressing melanoma cell can be resolved with help of bortezomib

Chemoresistance of PRAME-expressing melanoma cell can be resolved with help of bortezomib

Background. PRAME gene spontaneous expression is frequently observed in a cancer cell. The protein encoded by this gene increases  the viability of tumour cell. NF-κB signalling pathway takes part in PRAME upregulation. It proposes, that stress conditions may increase the expression level of PRAME i...

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Bibliographic Details
Main Authors: V. A. Misyurin, D. V. Kalenichenko, A. A. Rudakova, Yu. P. Finashutina, N. A. Lyzhko, V. V. Tikhonova, L. A. Kesaeva, O. N. Solopova, A. Е. Misyurina, A. N. Velikanov, M. А. Baryshnikovа, A. V. Misyurin
Format: Article
Language:Russian
Published: ABV-press 2019-01-01
Series:Успехи молекулярной онкологии
Subjects:
prame
melanoma
cisplatin
bortezomib
dexamethasone
drug resistance
Online Access:https://umo.abvpress.ru/jour/article/view/183

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