A Computational Model for Predicting RNase H Domain of Retrovirus.

RNase H (RNH) is a pivotal domain in retrovirus to cleave the DNA-RNA hybrid for continuing retroviral replication. The crucial role indicates that RNH is a promising drug target for therapeutic intervention. However, annotated RNHs in UniProtKB database have still been insufficient for a good under...

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Hlavní autoři: Sijia Wu, Xinman Zhang, Jiuqiang Han
Médium: Článek
Jazyk:English
Vydáno: Public Library of Science (PLoS) 2016-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC5019361?pdf=render