A Computational Model for Predicting RNase H Domain of Retrovirus.
RNase H (RNH) is a pivotal domain in retrovirus to cleave the DNA-RNA hybrid for continuing retroviral replication. The crucial role indicates that RNH is a promising drug target for therapeutic intervention. However, annotated RNHs in UniProtKB database have still been insufficient for a good under...
Hlavní autoři: | , , |
---|---|
Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2016-01-01
|
Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC5019361?pdf=render |