Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and Exercise

Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and Exercise

Nicotinamide adenine dinucleotide (NAD) is a versatile chemical compound serving as a coenzyme in metabolic pathways and as a substrate to support the enzymatic functions of sirtuins (SIRTs), poly (ADP-ribose) polymerase-1 (PARP-1), and cyclic ADP ribose hydrolase (CD38). Under normal physiological...

Full description

Bibliographic Details
Main Authors:	Li Li Ji, Dongwook Yeo
Format:	Article
Language:	English
Published:	MDPI AG 2022-02-01
Series:	Cells
Subjects:	aging exercise NAD+ mitochondria skeletal muscle sirtuin
Online Access:	https://www.mdpi.com/2073-4409/11/4/710

Similar Items

Regular exercise effectively protects against the aging-associated decline in skeletal muscle NAD content
by: Sabina Chubanava, et al.
Published: (2023-03-01)

Age-related changes in skeletal muscle mitochondria: the role of exercise
by: Dae Yun Seo, et al.
Published: (2016-09-01)

Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia
by: Colin Harper, et al.
Published: (2021-02-01)

Exercise, mitochondrial dysfunction and inflammasomes in skeletal muscle
by: Mikhaela B. Slavin, et al.
Published: (2024-02-01)

Sarcopenia and Muscle Aging: A Brief Overview
by: Tam Dao, et al.
Published: (2020-12-01)

Impact of Exercise and Aging on Mitochondrial Homeostasis in Skeletal Muscle: Roles of ROS and Epigenetics
by: Jialin Li, et al.
Published: (2022-06-01)

NAMPT-Mediated NAD+ Biosynthesis Is Essential for Vision In Mice
by: Jonathan B. Lin, et al.
Published: (2016-09-01)

Exercise Training Protects against Atorvastatin-Induced Skeletal Muscle Dysfunction and Mitochondrial Dysfunction in the Skeletal Muscle of Rats
by: Dae Yun Seo, et al.
Published: (2020-07-01)

The Central Role of the NAD+ Molecule in the Development of Aging and the Prevention of Chronic Age-Related Diseases: Strategies for NAD+ Modulation
by: Borut Poljšak, et al.
Published: (2023-02-01)

Doxorubicin-dependent skeletal muscle atrophy: exercise and mitochondrial dysfunction
by: Gökhan Burçin Kubat, et al.
Published: (2024-02-01)

Aged Nicotinamide Riboside Kinase 2 Deficient Mice Present an Altered Response to Endurance Exercise Training
by: Robin Deloux, et al.
Published: (2018-09-01)

Age-associated inflammation and implications for skeletal muscle responses to exercise
by: Hawley E. Kunz, et al.
Published: (2023-06-01)

Role of NAD+ in regulating cellular and metabolic signaling pathways
by: Sara Amjad, et al.
Published: (2021-07-01)

Exercise Training Differentially Affects Skeletal Muscle Mitochondria in Rats with Inherited High or Low Exercise Capacity
by: Estelle Heyne, et al.
Published: (2024-02-01)

Cellular and Mitochondrial NAD Homeostasis in Health and Disease
by: Jaylyn Waddell, et al.
Published: (2023-05-01)

Hsp60 in Skeletal Muscle Fiber Biogenesis and Homeostasis: From Physical Exercise to Skeletal Muscle Pathology
by: Antonella Marino Gammazza, et al.
Published: (2018-11-01)

Editorial: Redox Regulation in Skeletal Muscle Aging and Exercise
by: Brian eMcDonagh
Published: (2016-01-01)

Physical exercise elicits UPRmt in the skeletal muscle: The role of c-Jun N-terminal kinase
by: Rodrigo Stellzer Gaspar, et al.
Published: (2023-12-01)

Skeletal Muscle Mitochondrial Energetic Efficiency and Aging
by: Raffaella Crescenzo, et al.
Published: (2015-05-01)

The effect of 4-hexylresorinol administration on NAD+ level and SIRT activity in Saos-2 cells
by: In-Song Lee, et al.
Published: (2021-11-01)

Role of Exercise in Skeletal Muscle Atrophy: A Mechanistic Investigation
by: Dae Yun Seo, et al.
Published: (2020-08-01)

Cellular and Molecular Mechanisms of the Production of Free Radicals during Exercise and Their Function on Skeletal Muscles
by: Fatemeh Heyat
Published: (2017-05-01)

Cellular and Molecular Mechanisms of the Production of Free Radicals during Exercise and Their Function on Skeletal Muscles
by: Fatemeh Heyat
Published: (2017-06-01)

Aerobic Exercise Affects Myostatin Expression in Aged Rat Skeletal Muscles: A Possibility of Antiaging Effects of Aerobic Exercise Related With Pelvic Floor Muscle and Urethral Rhabdosphincter
by: Il Gyu Ko, et al.
Published: (2014-06-01)

Exercise-Induced Mitohormesis for the Maintenance of Skeletal Muscle and Healthspan Extension
by: Robert V. Musci, et al.
Published: (2019-07-01)

Impact of Oxidative Stress on Exercising Skeletal Muscle
by: Peter Steinbacher, et al.
Published: (2015-04-01)

NAD<sup>+</sup> Precursors Repair Mitochondrial Function in Diabetes and Prevent Experimental Diabetic Neuropathy
by: Krish Chandrasekaran, et al.
Published: (2022-04-01)

Exercise and Caloric Restriction Exert Different Benefits on Skeletal Muscle Metabolism in Aging Condition
by: Chanisa Thonusin, et al.
Published: (2023-12-01)

The impact of statin therapy and aerobic exercise training on skeletal muscle and whole-body aerobic capacity
by: Jill M. Slade, et al.
Published: (2021-05-01)

Exercise and the Cisd2 Prolongevity Gene: Two Promising Strategies to Delay the Aging of Skeletal Muscle
by: Yuan-Chi Teng, et al.
Published: (2020-11-01)

NAD+: A key metabolic regulator with great therapeutic potential for myocardial infarction via Sirtuins family
by: Wei Yao, et al.
Published: (2023-11-01)

Mitochondrial Properties in Skeletal Muscle Fiber
by: Han Dong, et al.
Published: (2023-08-01)

MITOCHONDRIA QUALITY CONTROL AND MUSCLE MASS MAINTENANCE
by: Vanina eRomanello, et al.
Published: (2016-01-01)

Acute resistance exercise training does not augment mitochondrial remodelling in master athletes or untrained older adults
by: Ryan Neil Marshall, et al.
Published: (2023-01-01)

No effect of five days of bed rest or short‐term resistance exercise prehabilitation on markers of skeletal muscle mitochondrial content and dynamics in older adults
by: Ryan N. Marshall, et al.
Published: (2022-07-01)

Mitochondrial Adaptations in Elderly and Young Men Skeletal Muscle Following 2 Weeks of Bed Rest and Rehabilitation
by: Alessia Buso, et al.
Published: (2019-05-01)

The Role of Nrf2 in Skeletal Muscle on Exercise Capacity
by: Yu Kitaoka
Published: (2021-10-01)

Redox control of signalling responses to contractile activity and aging in skeletal muscle
by: Malcolm J Jackson
Published: (2023-10-01)

Exercise, but Not Metformin Prevents Loss of Muscle Function Due to Doxorubicin in Mice Using an In Situ Method
by: Amy D. Mackay, et al.
Published: (2021-08-01)

Adaptations in Mitochondrial Enzymatic Activity Occurs Independent of Genomic Dosage in Response to Aerobic Exercise Training and Deconditioning in Human Skeletal Muscle
by: Andreas M. Fritzen, et al.
Published: (2019-03-01)