An Up-To-Date View at the Etiopathogenesis of Keratoconus
The etiology of keratoconus is unknown. Different factors have been shown to play a role in the etiology and pathogenesis. Both genetic and environmental factors are thought to play a role in the formation of the disease. The research studies that have been done so far suggest a multifactorial phe...
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2011-10-01
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| Series: | Türk Oftalmoloji Dergisi |
| Subjects: | |
| Online Access: | http://www.oftalmoloji.org/article_1380/An-Up-to-date-View-At-The-Etiopathogenesis-Of-Keratoconus |
| _version_ | 1797912002071363584 |
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| author | Hilmi Or |
| author_facet | Hilmi Or |
| author_sort | Hilmi Or |
| collection | DOAJ |
| description | The etiology of keratoconus is unknown. Different factors have been shown to play a role in the etiology and pathogenesis. Both genetic
and environmental factors are thought to play a role in the formation of the disease. The research studies that have been done so far
suggest a multifactorial phenotypic expression. Research studies have been conducted to find the possible genetic factors for keratoconus
in various aspects: Analysis of diseases coexisting with keratoconus, gene research, protein and enzyme studies are some of the studies in
this direction. Recent research in the pathophysiology of keratoconus on the basis of cell has shown oxidative stress as a cause of ectatic
changes. In the etiology apart from genetic factors, hormones and hormonal balances are investigated, as well as chronic trauma (contact
lens use and eye rubbing) is examined as a possible cause. (Turk J Oph thal mol 2011; 41: 339-47) |
| first_indexed | 2024-04-10T11:49:32Z |
| format | Article |
| id | doaj.art-87d8a8e2c86341f0a432de4822eaa83f |
| institution | Directory Open Access Journal |
| issn | 1300-0659 2147-2661 |
| language | English |
| last_indexed | 2024-04-10T11:49:32Z |
| publishDate | 2011-10-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Oftalmoloji Dergisi |
| spelling | doaj.art-87d8a8e2c86341f0a432de4822eaa83f2023-02-15T16:17:11ZengGalenos YayineviTürk Oftalmoloji Dergisi1300-06592147-26612011-10-0141533934710.4274/tjo.41.75047An Up-To-Date View at the Etiopathogenesis of KeratoconusHilmi Or0Özel Muayenehane, İstanbul, TürkiyeThe etiology of keratoconus is unknown. Different factors have been shown to play a role in the etiology and pathogenesis. Both genetic and environmental factors are thought to play a role in the formation of the disease. The research studies that have been done so far suggest a multifactorial phenotypic expression. Research studies have been conducted to find the possible genetic factors for keratoconus in various aspects: Analysis of diseases coexisting with keratoconus, gene research, protein and enzyme studies are some of the studies in this direction. Recent research in the pathophysiology of keratoconus on the basis of cell has shown oxidative stress as a cause of ectatic changes. In the etiology apart from genetic factors, hormones and hormonal balances are investigated, as well as chronic trauma (contact lens use and eye rubbing) is examined as a possible cause. (Turk J Oph thal mol 2011; 41: 339-47)http://www.oftalmoloji.org/article_1380/An-Up-to-date-View-At-The-Etiopathogenesis-Of-KeratoconusKeratoconusetiologypathogenesis |
| spellingShingle | Hilmi Or An Up-To-Date View at the Etiopathogenesis of Keratoconus Türk Oftalmoloji Dergisi Keratoconus etiology pathogenesis |
| title | An Up-To-Date View at the Etiopathogenesis of Keratoconus |
| title_full | An Up-To-Date View at the Etiopathogenesis of Keratoconus |
| title_fullStr | An Up-To-Date View at the Etiopathogenesis of Keratoconus |
| title_full_unstemmed | An Up-To-Date View at the Etiopathogenesis of Keratoconus |
| title_short | An Up-To-Date View at the Etiopathogenesis of Keratoconus |
| title_sort | up to date view at the etiopathogenesis of keratoconus |
| topic | Keratoconus etiology pathogenesis |
| url | http://www.oftalmoloji.org/article_1380/An-Up-to-date-View-At-The-Etiopathogenesis-Of-Keratoconus |
| work_keys_str_mv | AT hilmior anuptodateviewattheetiopathogenesisofkeratoconus AT hilmior uptodateviewattheetiopathogenesisofkeratoconus |