A Comprehensive Review of miRNAs and Their Epigenetic Effects in Glioblastoma

A Comprehensive Review of miRNAs and Their Epigenetic Effects in Glioblastoma

Glioblastoma is the most aggressive form of brain tumor originating from glial cells with a maximum life expectancy of 14.6 months. Despite the establishment of multiple promising therapies, the clinical outcome of glioblastoma patients is abysmal. Drug resistance has been identified as a major fact...

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Bibliographic Details
Main Authors: Hera Hasan, Mohammad Afzal, Javier S. Castresana, Mehdi H. Shahi
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cells
Subjects:
glioblastoma
miRNA
temozolomide
epigenetics
DNA methylation
Online Access:https://www.mdpi.com/2073-4409/12/12/1578

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