Lifting the mask: identification of new small molecule inhibitors of uropathogenic Escherichia coli group 2 capsule biogenesis.

Uropathogenic Escherichia coli (UPEC) is the leading cause of community-acquired urinary tract infections (UTIs), with over 100 million UTIs occurring annually throughout the world. Increasing antimicrobial resistance among UPEC limits ambulatory care options, delays effective treatment, and may inc...

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Bibliographic Details
Main Authors: Carlos C Goller, Mehreen Arshad, James W Noah, Subramaniam Ananthan, Carrie W Evans, N Miranda Nebane, Lynn Rasmussen, Melinda Sosa, Nichole A Tower, E Lucile White, Benjamin Neuenswander, Patrick Porubsky, Brooks E Maki, Steven A Rogers, Frank Schoenen, Patrick C Seed
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4077706?pdf=render