Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species

Alternative Polyadenylation and Differential Regulation of Ucp1: Implications for Brown Adipose Tissue Thermogenesis Across Species

Brown adipose tissue (BAT) is a thermogenic organ owing to its unique expression of uncoupling protein 1 (UCP1), which is a proton channel in the inner mitochondrial membrane used to dissipate the proton gradient and uncouple the electron transport chain to generate heat instead of adenosine triphos...

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Bibliographic Details
Main Authors: Wen-Hsin Lu, Yao-Ming Chang, Yi-Shuian Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Pediatrics
Subjects:
alternative polyadenylation
brown adipose tissue
thermogenesis
transcriptional control
translational control
uncoupling protein 1
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2020.612279/full

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