Chimeric Antigen Receptor T Cell and Chimeric Antigen Receptor NK Cell Therapy in Pediatric and Adult High-Grade Glioma—Recent Advances

Chimeric Antigen Receptor T Cell and Chimeric Antigen Receptor NK Cell Therapy in Pediatric and Adult High-Grade Glioma—Recent Advances

High-grade gliomas (HGG) account for approximately 10% of central nervous system (CNS) tumors in children and 25% of CNS tumors in adults. Despite their rare occurrence, HGG are a significant clinical problem. The standard therapeutic procedure in both pediatric and adult patients with HGG is the su...

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Bibliographic Details
Main Authors: Adrian Kowalczyk, Julia Zarychta, Anna Marszołek, Joanna Zawitkowska, Monika Lejman
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
CAR-T
CAR-NK
high-grade glioma
tumor immunosuppressive microenvironment
Online Access:https://www.mdpi.com/2072-6694/16/3/623

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