The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease

The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease

Abstract Astrocyte dysfunction has previously been linked to multiple neurodegenerative disorders including Parkinson’s disease (PD). Among their many roles, astrocytes are mediators of the brain immune response, and astrocyte reactivity is a pathological feature of PD. They are also involved in the...

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Bibliographic Details
Main Authors: A. de Rus Jacquet, M. Alpaugh, H. L. Denis, J. L. Tancredi, M. Boutin, J. Decaestecker, C. Beauparlant, L. Herrmann, M. Saint-Pierre, M. Parent, A. Droit, S. Breton, F. Cicchetti
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39038-8

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