Demystifying the role of the Mantoux test in ocular tuberculosis

Context: The diagnosis and management of ocular tuberculosis (OTB) is largely a mystery, and the fact that it is a great imitator of various ocular pathologies adds to the difficulty in the diagnosis of patients. Aims: The aim of this study was to assess the role of the Mantoux test in the diagnosis...

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Main Authors: Mayur R Moreker, Avya Bansal, Sunila Jaggi, Sonali Shah, Asmita Sakle, Shilpa R Moreker
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Clinical Ophthalmology and Research
Subjects:
Online Access:http://www.jcor.in/article.asp?issn=2320-3897;year=2023;volume=11;issue=3;spage=194;epage=198;aulast=Moreker
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author Mayur R Moreker
Avya Bansal
Sunila Jaggi
Sonali Shah
Asmita Sakle
Shilpa R Moreker
author_facet Mayur R Moreker
Avya Bansal
Sunila Jaggi
Sonali Shah
Asmita Sakle
Shilpa R Moreker
author_sort Mayur R Moreker
collection DOAJ
description Context: The diagnosis and management of ocular tuberculosis (OTB) is largely a mystery, and the fact that it is a great imitator of various ocular pathologies adds to the difficulty in the diagnosis of patients. Aims: The aim of this study was to assess the role of the Mantoux test in the diagnosis of OTB. Settings and Design: This was a retrospective chart review of patients who were diagnosed to have and treated as OTB in 1 year at our tertiary care center in Western India. Methods: The study population included 34 patients who presented to us and were diagnosed to have OTB, using standards published by the Department of Health Research, Ministry of Health and Family Welfare, Government of India, and the Indian Council of Medical Research. Results: A total of 34 patients were diagnosed to have OTB in the study period of 1 year between January 1, 2021, and December 31, 2021. Of these 34 patients; 14 were male and 20 were female. The Mantoux test had been done in 32/34 patients. It was positive in 26 patients and negative in six patients. Looking specifically at the six patients in whom the Mantoux was negative, apart from having ocular signs of tuberculosis (TB), they had positive findings suggestive of old/active TB on contrast-enhanced chest computed tomography scan. Of the 34 patients, only five patients were treated based only on the clinical signs of OTB with only a positive Mantoux test, but even they all showed a response to treatment. Conclusions: There is a definite role of the Mantoux test when interpreted considering the clinical phenotype and radiology findings in OTB.
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spelling doaj.art-87f308560459408cb5bbc93337aa000b2023-10-30T09:27:31ZengWolters Kluwer Medknow PublicationsJournal of Clinical Ophthalmology and Research2320-38972023-01-0111319419810.4103/jcor.jcor_62_23Demystifying the role of the Mantoux test in ocular tuberculosisMayur R MorekerAvya BansalSunila JaggiSonali ShahAsmita SakleShilpa R MorekerContext: The diagnosis and management of ocular tuberculosis (OTB) is largely a mystery, and the fact that it is a great imitator of various ocular pathologies adds to the difficulty in the diagnosis of patients. Aims: The aim of this study was to assess the role of the Mantoux test in the diagnosis of OTB. Settings and Design: This was a retrospective chart review of patients who were diagnosed to have and treated as OTB in 1 year at our tertiary care center in Western India. Methods: The study population included 34 patients who presented to us and were diagnosed to have OTB, using standards published by the Department of Health Research, Ministry of Health and Family Welfare, Government of India, and the Indian Council of Medical Research. Results: A total of 34 patients were diagnosed to have OTB in the study period of 1 year between January 1, 2021, and December 31, 2021. Of these 34 patients; 14 were male and 20 were female. The Mantoux test had been done in 32/34 patients. It was positive in 26 patients and negative in six patients. Looking specifically at the six patients in whom the Mantoux was negative, apart from having ocular signs of tuberculosis (TB), they had positive findings suggestive of old/active TB on contrast-enhanced chest computed tomography scan. Of the 34 patients, only five patients were treated based only on the clinical signs of OTB with only a positive Mantoux test, but even they all showed a response to treatment. Conclusions: There is a definite role of the Mantoux test when interpreted considering the clinical phenotype and radiology findings in OTB.http://www.jcor.in/article.asp?issn=2320-3897;year=2023;volume=11;issue=3;spage=194;epage=198;aulast=Morekerclinical phenotype of ocular tuberculosisextrapulmonary tuberculosismantoux testocular tuberculosisstandard treatment workflow for the management of intraocular tuberculosistuberculin skin test
spellingShingle Mayur R Moreker
Avya Bansal
Sunila Jaggi
Sonali Shah
Asmita Sakle
Shilpa R Moreker
Demystifying the role of the Mantoux test in ocular tuberculosis
Journal of Clinical Ophthalmology and Research
clinical phenotype of ocular tuberculosis
extrapulmonary tuberculosis
mantoux test
ocular tuberculosis
standard treatment workflow for the management of intraocular tuberculosis
tuberculin skin test
title Demystifying the role of the Mantoux test in ocular tuberculosis
title_full Demystifying the role of the Mantoux test in ocular tuberculosis
title_fullStr Demystifying the role of the Mantoux test in ocular tuberculosis
title_full_unstemmed Demystifying the role of the Mantoux test in ocular tuberculosis
title_short Demystifying the role of the Mantoux test in ocular tuberculosis
title_sort demystifying the role of the mantoux test in ocular tuberculosis
topic clinical phenotype of ocular tuberculosis
extrapulmonary tuberculosis
mantoux test
ocular tuberculosis
standard treatment workflow for the management of intraocular tuberculosis
tuberculin skin test
url http://www.jcor.in/article.asp?issn=2320-3897;year=2023;volume=11;issue=3;spage=194;epage=198;aulast=Moreker
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