Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation
PurposeTo provide a perspective and surgical video demonstration of peripheral corneal ulceration and perforation managed with multilayered amniotic membrane transplantation.Case ReportsCase 1 describes a 48-year-old female with progressive redness and pain, and an inferonasal corneal thinning and p...
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2022.836873/full |
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| author | Maryam Eslami Blanca Benito-Pascual Blanca Benito-Pascual Saadiah Goolam Saadiah Goolam Tanya Trinh Tanya Trinh Tanya Trinh Greg Moloney Greg Moloney Greg Moloney Greg Moloney |
| author_facet | Maryam Eslami Blanca Benito-Pascual Blanca Benito-Pascual Saadiah Goolam Saadiah Goolam Tanya Trinh Tanya Trinh Tanya Trinh Greg Moloney Greg Moloney Greg Moloney Greg Moloney |
| author_sort | Maryam Eslami |
| collection | DOAJ |
| description | PurposeTo provide a perspective and surgical video demonstration of peripheral corneal ulceration and perforation managed with multilayered amniotic membrane transplantation.Case ReportsCase 1 describes a 48-year-old female with progressive redness and pain, and an inferonasal corneal thinning and perforation in the left eye from peripheral ulcerative keratitis. She underwent conjunctival recession with amniotic membrane inlay and onlay (Sandwich technique) transplantation. The amniotic membrane integrated well, and her Snellen visual acuity improved from 6/21 preoperatively to 6/9 at 3 months post op. Case 2 describes a 78-year-old male with redness and pain with temporal corneal thinning bilaterally and perforation in the right eye from peripheral ulcerative keratitis. Both eyes underwent similar surgical intervention with smooth integration of the amniotic membrane in the cornea and improvement in the visual acuity. Both patients were also started on systemic immunosuppression in collaboration with the rheumatology team.ConclusionWe report successful use of multilayered amniotic membrane transplantation for the treatment of corneal ulceration and perforation. The authors believe the simplicity of the surgical technique, easier access to amniotic membrane tissue, and lower induced post-operative astigmatism all provide advantages over alternative treatment modalities. |
| first_indexed | 2024-12-12T22:30:41Z |
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| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-12-12T22:30:41Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-87f351a5cfa041359ab455025a25561a2022-12-22T00:09:37ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2022-04-01910.3389/fmed.2022.836873836873Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal PerforationMaryam Eslami0Blanca Benito-Pascual1Blanca Benito-Pascual2Saadiah Goolam3Saadiah Goolam4Tanya Trinh5Tanya Trinh6Tanya Trinh7Greg Moloney8Greg Moloney9Greg Moloney10Greg Moloney11Department of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, CanadaSydney Eye Hospital, Sydney, NSW, AustraliaSave Sight Institute, University of Sydney, Sydney, NSW, AustraliaSydney Eye Hospital, Sydney, NSW, AustraliaSave Sight Institute, University of Sydney, Sydney, NSW, AustraliaSydney Eye Hospital, Sydney, NSW, AustraliaSave Sight Institute, University of Sydney, Sydney, NSW, AustraliaMosman Eye Centre and Narellan Eye Specialists, Sydney, NSW, AustraliaDepartment of Ophthalmology and Visual Sciences, University of British Columbia, Vancouver, BC, CanadaSydney Eye Hospital, Sydney, NSW, AustraliaSave Sight Institute, University of Sydney, Sydney, NSW, AustraliaMosman Eye Centre and Narellan Eye Specialists, Sydney, NSW, AustraliaPurposeTo provide a perspective and surgical video demonstration of peripheral corneal ulceration and perforation managed with multilayered amniotic membrane transplantation.Case ReportsCase 1 describes a 48-year-old female with progressive redness and pain, and an inferonasal corneal thinning and perforation in the left eye from peripheral ulcerative keratitis. She underwent conjunctival recession with amniotic membrane inlay and onlay (Sandwich technique) transplantation. The amniotic membrane integrated well, and her Snellen visual acuity improved from 6/21 preoperatively to 6/9 at 3 months post op. Case 2 describes a 78-year-old male with redness and pain with temporal corneal thinning bilaterally and perforation in the right eye from peripheral ulcerative keratitis. Both eyes underwent similar surgical intervention with smooth integration of the amniotic membrane in the cornea and improvement in the visual acuity. Both patients were also started on systemic immunosuppression in collaboration with the rheumatology team.ConclusionWe report successful use of multilayered amniotic membrane transplantation for the treatment of corneal ulceration and perforation. The authors believe the simplicity of the surgical technique, easier access to amniotic membrane tissue, and lower induced post-operative astigmatism all provide advantages over alternative treatment modalities.https://www.frontiersin.org/articles/10.3389/fmed.2022.836873/fullamniotic membrane transplantationcorneal perforationperipheral ulcerative keratitiscorneal ulcerationtectonic graft repair |
| spellingShingle | Maryam Eslami Blanca Benito-Pascual Blanca Benito-Pascual Saadiah Goolam Saadiah Goolam Tanya Trinh Tanya Trinh Tanya Trinh Greg Moloney Greg Moloney Greg Moloney Greg Moloney Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation Frontiers in Medicine amniotic membrane transplantation corneal perforation peripheral ulcerative keratitis corneal ulceration tectonic graft repair |
| title | Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation |
| title_full | Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation |
| title_fullStr | Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation |
| title_full_unstemmed | Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation |
| title_short | Case Report: Use of Amniotic Membrane for Tectonic Repair of Peripheral Ulcerative Keratitis With Corneal Perforation |
| title_sort | case report use of amniotic membrane for tectonic repair of peripheral ulcerative keratitis with corneal perforation |
| topic | amniotic membrane transplantation corneal perforation peripheral ulcerative keratitis corneal ulceration tectonic graft repair |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2022.836873/full |
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