Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients
Background Red cell distribution width (RDW) is a prognostic marker in vascular diseases. While increased RDW predicts mortality and outcomes after ischemic stroke, evidence regarding its prognostic significance in stroke rehabilitation is lacking. Thus, the present study investigated the relationsh...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Korea Geriatrics Society
2020-09-01
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| Series: | Annals of Geriatric Medicine and Research |
| Subjects: | |
| Online Access: | http://www.e-agmr.org/upload/pdf/agmr-20-0042.pdf |
| _version_ | 1818991809422950400 |
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| author | Eduard Zalyesov Inna Shugaev Yanna Prokopov Ron Shahory Stefan Chirmicci Efraim Aizen |
| author_facet | Eduard Zalyesov Inna Shugaev Yanna Prokopov Ron Shahory Stefan Chirmicci Efraim Aizen |
| author_sort | Eduard Zalyesov |
| collection | DOAJ |
| description | Background Red cell distribution width (RDW) is a prognostic marker in vascular diseases. While increased RDW predicts mortality and outcomes after ischemic stroke, evidence regarding its prognostic significance in stroke rehabilitation is lacking. Thus, the present study investigated the relationship of RDW with stroke, orthopedic, and deconditioning rehabilitation outcomes. Methods This prospective comparative study included three groups (stroke, orthopedic, and deconditioning) of older adult patients hospitalized for rehabilitation. The patients in each group were divided into two subgroups according to whether they had high (>14.5%) or normal (≤14.5%) RDW levels on admission. Functional outcome was assessed by total and motor FIM (Functional Independence Measure) score changes and efficiency at admission and on discharge. Results Of the 234 eligible patients, 108 (46.2%) had high RDW. Of the 50 stroke rehabilitation patients, 13 (26%) had high RDW. FIM change and efficiency scores were significantly lower in patients with high RDW only in the stroke rehabilitation group. However, multiple linear regression analysis showed that high RDW was not independently associated with total and motor FIM gain or total and motor FIM efficiency. Conclusion High RDW levels on admission to rehabilitation were associated with poor rehabilitation outcome in stroke patients but were not an independent risk factor for rehabilitation outcomes. |
| first_indexed | 2024-12-20T20:16:10Z |
| format | Article |
| id | doaj.art-8800cd0ec6ce452fbd184ed53d660854 |
| institution | Directory Open Access Journal |
| issn | 2508-4798 2508-4909 |
| language | English |
| last_indexed | 2024-12-20T20:16:10Z |
| publishDate | 2020-09-01 |
| publisher | Korea Geriatrics Society |
| record_format | Article |
| series | Annals of Geriatric Medicine and Research |
| spelling | doaj.art-8800cd0ec6ce452fbd184ed53d6608542022-12-21T19:27:42ZengKorea Geriatrics SocietyAnnals of Geriatric Medicine and Research2508-47982508-49092020-09-0124321121710.4235/agmr.20.0042931Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke PatientsEduard Zalyesov0Inna Shugaev1Yanna Prokopov2Ron Shahory3Stefan Chirmicci4Efraim Aizen5 Fliman Geriatric Rehabilitation Hospital, Haifa, Israel Fliman Geriatric Rehabilitation Hospital, Haifa, Israel Fliman Geriatric Rehabilitation Hospital, Haifa, Israel Fliman Geriatric Rehabilitation Hospital, Haifa, Israel Fliman Geriatric Rehabilitation Hospital, Haifa, Israel Fliman Geriatric Rehabilitation Hospital, Haifa, IsraelBackground Red cell distribution width (RDW) is a prognostic marker in vascular diseases. While increased RDW predicts mortality and outcomes after ischemic stroke, evidence regarding its prognostic significance in stroke rehabilitation is lacking. Thus, the present study investigated the relationship of RDW with stroke, orthopedic, and deconditioning rehabilitation outcomes. Methods This prospective comparative study included three groups (stroke, orthopedic, and deconditioning) of older adult patients hospitalized for rehabilitation. The patients in each group were divided into two subgroups according to whether they had high (>14.5%) or normal (≤14.5%) RDW levels on admission. Functional outcome was assessed by total and motor FIM (Functional Independence Measure) score changes and efficiency at admission and on discharge. Results Of the 234 eligible patients, 108 (46.2%) had high RDW. Of the 50 stroke rehabilitation patients, 13 (26%) had high RDW. FIM change and efficiency scores were significantly lower in patients with high RDW only in the stroke rehabilitation group. However, multiple linear regression analysis showed that high RDW was not independently associated with total and motor FIM gain or total and motor FIM efficiency. Conclusion High RDW levels on admission to rehabilitation were associated with poor rehabilitation outcome in stroke patients but were not an independent risk factor for rehabilitation outcomes.http://www.e-agmr.org/upload/pdf/agmr-20-0042.pdfstrokered cell distribution widthrehabilitationrecovery of function |
| spellingShingle | Eduard Zalyesov Inna Shugaev Yanna Prokopov Ron Shahory Stefan Chirmicci Efraim Aizen Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients Annals of Geriatric Medicine and Research stroke red cell distribution width rehabilitation recovery of function |
| title | Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients |
| title_full | Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients |
| title_fullStr | Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients |
| title_full_unstemmed | Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients |
| title_short | Red Cell Distribution Width as a Predictor of Functional Outcome in Rehabilitation of Older Stroke Patients |
| title_sort | red cell distribution width as a predictor of functional outcome in rehabilitation of older stroke patients |
| topic | stroke red cell distribution width rehabilitation recovery of function |
| url | http://www.e-agmr.org/upload/pdf/agmr-20-0042.pdf |
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