Toosendanin inhibits proliferation and promotes apoptosis of gastrointestinal stromal tumor-T1 cells by down-regulating c-kit expression

Toosendanin inhibits proliferation and promotes apoptosis of gastrointestinal stromal tumor-T1 cells by down-regulating c-kit expression

Objective To investigate the effects of toosendanin (TSN) on the proliferation and apoptosis of gastrointestinal stromal tumor (GIST) cells, and to explore the underlying mechanisms. Methods GIST-T1 cells were treated with TSN at different concentrations, and then CCK-8 assay was used to detect the...

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Bibliographic Details
Main Authors: HU Xiaoyu, YANG Wensheng, KANG Zhengyu
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-07-01
Series:Di-san junyi daxue xuebao
Subjects:
gastrointestinal stromal tumor
toosendanin
imatinib
cell proliferation
apoptosis
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202012232.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202012232.htm

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