Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac; <1%) snRNPs. The high conservation of minor introns, typically one amidst many major introns in several hundred genes, despite their poor splicing, has been a long-sta...

Full description

Bibliographic Details
Main Authors: Ihab Younis, Kimberly Dittmar, Wei Wang, Shawn W Foley, Michael G Berg, Karen Y Hu, Zhi Wei, Lili Wan, Gideon Dreyfuss
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-07-01
Series:eLife
Subjects:
snRNA
U6atac
splicing
gene regulation
Online Access:https://elifesciences.org/articles/00780

Similar Items

Similar Items