Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy

Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy

Globally, it is estimated that 43 million people are living with human immunodeficiency virus type 1 (HIV-1), and there are more than 600,000 acquired immunodeficiency syndrome (AIDS)-related deaths in 2020. The only way to increase the life expectancy of these patients right now is to use combinati...

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Bibliographic Details
Main Authors: Ali Salimi-Jeda, Maryam Esghaei, Hossein keyvani, Farah Bokharaei-Salim, Ali Teimoori, Asghar Abdoli
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Heliyon
Subjects:
CRISPR/Cas9
Guide RNA
HIV
Prophylactic strategy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022017716

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