The safety of in‐office laryngologic procedures during active antithrombotic therapy
Abstract Objectives To determine whether patients undergoing in‐office laryngologic procedures on antithrombotic therapy are at increased risk for treatment‐related complications. Methods Patients were those who underwent at least one in‐office laryngologic procedure with any of three fellowship‐tra...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-10-01
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| Series: | Laryngoscope Investigative Otolaryngology |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/lio2.451 |
| _version_ | 1818058186118135808 |
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| author | Jeffrey M. Straub Kevin A. Calamari Timothy J. Shin Sarah A. Janse Lowell A. Forrest Brad W. deSilva Laura A. Matrka |
| author_facet | Jeffrey M. Straub Kevin A. Calamari Timothy J. Shin Sarah A. Janse Lowell A. Forrest Brad W. deSilva Laura A. Matrka |
| author_sort | Jeffrey M. Straub |
| collection | DOAJ |
| description | Abstract Objectives To determine whether patients undergoing in‐office laryngologic procedures on antithrombotic therapy are at increased risk for treatment‐related complications. Methods Patients were those who underwent at least one in‐office laryngologic procedure with any of three fellowship‐trained laryngologists. Procedures were identified by current procedural terminology (CPT) code and included biopsies, excisions, laser ablations, and injections (therapeutic and augmentative). Patients were divided into two groups based on the use of antithrombotic therapy at the time of their procedure. Retrospective chart review was performed to identify any complications, with an average follow‐up of 186 days. Results Five hundred‐sixty‐four unique individuals were identified with ages ranging from 18 to 93 years old and with a relatively even distribution between females (45%) and males (55%). They underwent 647 procedures in total, 310 of which were performed while on some form of antithrombotic therapy. Sixteen procedures were associated with complications either during or after the procedure. In comparing overall complication rates, there was no significant difference between non‐antithrombotic (2.4%) and antithrombotic (3.3%) cohorts (OR 1.09, 95% CI [0.46‐2.60], P = .8454). Conclusions In spite of known risks in other settings, antithrombotic agents do not appear to confer increased risk of treatment‐related complications during in‐office laryngologic procedures, obviating the need for cessation of therapy prior to these interventions. Level of evidence 4. |
| first_indexed | 2024-12-10T12:56:37Z |
| format | Article |
| id | doaj.art-881134b5fdef4afbae18e3125f44f428 |
| institution | Directory Open Access Journal |
| issn | 2378-8038 |
| language | English |
| last_indexed | 2024-12-10T12:56:37Z |
| publishDate | 2020-10-01 |
| publisher | Wiley |
| record_format | Article |
| series | Laryngoscope Investigative Otolaryngology |
| spelling | doaj.art-881134b5fdef4afbae18e3125f44f4282022-12-22T01:48:05ZengWileyLaryngoscope Investigative Otolaryngology2378-80382020-10-015589089410.1002/lio2.451The safety of in‐office laryngologic procedures during active antithrombotic therapyJeffrey M. Straub0Kevin A. Calamari1Timothy J. Shin2Sarah A. Janse3Lowell A. Forrest4Brad W. deSilva5Laura A. Matrka6Department of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USADepartment of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USADepartment of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USADepartment of Biomedical Informatics The Ohio State University Columbus Ohio USADepartment of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USADepartment of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USADepartment of Otolaryngology—Head and Neck Surgery The Ohio State University Columbus Ohio USAAbstract Objectives To determine whether patients undergoing in‐office laryngologic procedures on antithrombotic therapy are at increased risk for treatment‐related complications. Methods Patients were those who underwent at least one in‐office laryngologic procedure with any of three fellowship‐trained laryngologists. Procedures were identified by current procedural terminology (CPT) code and included biopsies, excisions, laser ablations, and injections (therapeutic and augmentative). Patients were divided into two groups based on the use of antithrombotic therapy at the time of their procedure. Retrospective chart review was performed to identify any complications, with an average follow‐up of 186 days. Results Five hundred‐sixty‐four unique individuals were identified with ages ranging from 18 to 93 years old and with a relatively even distribution between females (45%) and males (55%). They underwent 647 procedures in total, 310 of which were performed while on some form of antithrombotic therapy. Sixteen procedures were associated with complications either during or after the procedure. In comparing overall complication rates, there was no significant difference between non‐antithrombotic (2.4%) and antithrombotic (3.3%) cohorts (OR 1.09, 95% CI [0.46‐2.60], P = .8454). Conclusions In spite of known risks in other settings, antithrombotic agents do not appear to confer increased risk of treatment‐related complications during in‐office laryngologic procedures, obviating the need for cessation of therapy prior to these interventions. Level of evidence 4.https://doi.org/10.1002/lio2.451antithromboticscomplicationsin‐officelaryngologicprocedures |
| spellingShingle | Jeffrey M. Straub Kevin A. Calamari Timothy J. Shin Sarah A. Janse Lowell A. Forrest Brad W. deSilva Laura A. Matrka The safety of in‐office laryngologic procedures during active antithrombotic therapy Laryngoscope Investigative Otolaryngology antithrombotics complications in‐office laryngologic procedures |
| title | The safety of in‐office laryngologic procedures during active antithrombotic therapy |
| title_full | The safety of in‐office laryngologic procedures during active antithrombotic therapy |
| title_fullStr | The safety of in‐office laryngologic procedures during active antithrombotic therapy |
| title_full_unstemmed | The safety of in‐office laryngologic procedures during active antithrombotic therapy |
| title_short | The safety of in‐office laryngologic procedures during active antithrombotic therapy |
| title_sort | safety of in office laryngologic procedures during active antithrombotic therapy |
| topic | antithrombotics complications in‐office laryngologic procedures |
| url | https://doi.org/10.1002/lio2.451 |
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