Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India
Introduction: The salivary glands are subjected to various pathological conditions ranging from simple inflammation to most complex malignant lesions. Majority of these lesions can be diagnosed by simple histopathological examination. But, as these salivary gland lesions are not common, the inci...
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JCDR Research and Publications Pvt. Ltd.
2022-07-01
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| Series: | National Journal of Laboratory Medicine |
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| author | Sanuvada Vijay Rama Raja Sekhar Regidi Swathi Ratnam B Gouthami B RAVICHANDRA |
| author_facet | Sanuvada Vijay Rama Raja Sekhar Regidi Swathi Ratnam B Gouthami B RAVICHANDRA |
| author_sort | Sanuvada Vijay Rama Raja Sekhar |
| collection | DOAJ |
| description | Introduction: The salivary glands are subjected to various
pathological conditions ranging from simple inflammation to
most complex malignant lesions. Majority of these lesions can
be diagnosed by simple histopathological examination. But, as
these salivary gland lesions are not common, the incidence of
these varies in different geographic locations.
Aim: To study the spectrum of different salivary gland lesions
and demographic data in a tertiary care hospital serving northeast coastal area of Andhra Pradesh.
Materials and Methods: This was a retrospective study
conducted in Great Eastern Medical School and Hospital,
Srikakulam, Andhra Pradesh, India. Total of 85 salivary gland
lesions were analysed for a period of four years (December
2015 to November 2019). From the records of Histopathology,
Department of Pathology, data was retrieved. Typing of the
salivary gland tumours were done using sections stained with
Haematoxylin and Eosin (H&E). All the cases were analysed and
divided according to the demographics and histological type.
Descriptive statistics were used and data was tabulated in
frequency and percentages.
Results: A total of 85 salivary gland lesions were studied, of which
14 (16%) were non neoplastic and 71 (84%) were neoplastic in
nature. Among the neoplastic lesions, 56 (66%) were benign and
15 (18%) were malignant. There was slight male preponderance
with a ratio of M:F=1.3:1. Majority of the tumours occurred in
parotid gland (73), followed by submandibular gland (7) and
minor salivary glands (5). All the tumours were classified and
graded according to World Health Organisation (WHO), while
Brandwein Grading System was followed for mucoepidermoid
carcinoma. Pleomorphic adenoma was the most frequent benign
tumour and mucoepidermoid carcinoma was the most common
malignant tumour.
Conclusion: Though benign salivary gland tumours are more
frequently encountered in the present study, malignant salivary
gland tumours are not uncommon |
| first_indexed | 2024-04-11T13:33:24Z |
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| publisher | JCDR Research and Publications Pvt. Ltd. |
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| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-8811f92ea4b6414c9ab3e0110991b0db2022-12-22T04:21:43ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822022-07-01113626410.7860/NJLM/2022/55950.2651Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, IndiaSanuvada Vijay Rama Raja Sekhar0Regidi Swathi Ratnam1B Gouthami2B RAVICHANDRA3Associate Professor, Department of Pathology, GEMS Hospital, Srikakulam, Andhra Pradesh, IndiaAssistant Professor, Department of Pharmacology, GMC, Srikakulam, Andhra Pradesh, India.Assistant Professor, Department of Pathology, GEMS Hospital, Srikakulam, Andhra Pradesh, IndiAssistant Professor, Department of Pathology, GEMS Hospital, Srikakulam, Andhra Pradesh, India.Introduction: The salivary glands are subjected to various pathological conditions ranging from simple inflammation to most complex malignant lesions. Majority of these lesions can be diagnosed by simple histopathological examination. But, as these salivary gland lesions are not common, the incidence of these varies in different geographic locations. Aim: To study the spectrum of different salivary gland lesions and demographic data in a tertiary care hospital serving northeast coastal area of Andhra Pradesh. Materials and Methods: This was a retrospective study conducted in Great Eastern Medical School and Hospital, Srikakulam, Andhra Pradesh, India. Total of 85 salivary gland lesions were analysed for a period of four years (December 2015 to November 2019). From the records of Histopathology, Department of Pathology, data was retrieved. Typing of the salivary gland tumours were done using sections stained with Haematoxylin and Eosin (H&E). All the cases were analysed and divided according to the demographics and histological type. Descriptive statistics were used and data was tabulated in frequency and percentages. Results: A total of 85 salivary gland lesions were studied, of which 14 (16%) were non neoplastic and 71 (84%) were neoplastic in nature. Among the neoplastic lesions, 56 (66%) were benign and 15 (18%) were malignant. There was slight male preponderance with a ratio of M:F=1.3:1. Majority of the tumours occurred in parotid gland (73), followed by submandibular gland (7) and minor salivary glands (5). All the tumours were classified and graded according to World Health Organisation (WHO), while Brandwein Grading System was followed for mucoepidermoid carcinoma. Pleomorphic adenoma was the most frequent benign tumour and mucoepidermoid carcinoma was the most common malignant tumour. Conclusion: Though benign salivary gland tumours are more frequently encountered in the present study, malignant salivary gland tumours are not uncommonhttps://www.njlm.net/articles/PDF/2651/55950_CE[Ra1]_F_[SH]_PF1(PS_SS)_PFA(SHU)_PB(PS_SHU)_PN(SHU).pdfbenignhistopathologymalignantmucoepidermoid carcinomapleomorphic adenoma |
| spellingShingle | Sanuvada Vijay Rama Raja Sekhar Regidi Swathi Ratnam B Gouthami B RAVICHANDRA Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India National Journal of Laboratory Medicine benign histopathology malignant mucoepidermoid carcinoma pleomorphic adenoma |
| title | Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India |
| title_full | Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India |
| title_fullStr | Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India |
| title_full_unstemmed | Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India |
| title_short | Clinicopathological Spectrum of Salivary Gland Lesions- A Retrospective Study from Tertiary Care Research Institute, Andhra Pradesh, India |
| title_sort | clinicopathological spectrum of salivary gland lesions a retrospective study from tertiary care research institute andhra pradesh india |
| topic | benign histopathology malignant mucoepidermoid carcinoma pleomorphic adenoma |
| url | https://www.njlm.net/articles/PDF/2651/55950_CE[Ra1]_F_[SH]_PF1(PS_SS)_PFA(SHU)_PB(PS_SHU)_PN(SHU).pdf |
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