Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial
Background: COVID-19 pandemic could bring great impact upon the psychological statuses of post-partum women, but no clear evidence was provided yet as to COVID-19 would also affect their pain profile during post-partum period. We determined if pain and psychological vulnerabilities, obstetric factor...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-03-01
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| Series: | Heliyon |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024032717 |
| _version_ | 1797224275967475712 |
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| author | Chin Wen Tan Rehena Sultana Azriel Nicol Chang Hon Sen Tan Ban Leong Sng |
| author_facet | Chin Wen Tan Rehena Sultana Azriel Nicol Chang Hon Sen Tan Ban Leong Sng |
| author_sort | Chin Wen Tan |
| collection | DOAJ |
| description | Background: COVID-19 pandemic could bring great impact upon the psychological statuses of post-partum women, but no clear evidence was provided yet as to COVID-19 would also affect their pain profile during post-partum period. We determined if pain and psychological vulnerabilities, obstetric factors, and labor analgesia were associated with sub-acute pain after childbirth (SAPC; ongoing pain related to delivery at post-partum 4 weeks or more) during COVID-19 pandemic. Methods: We included women having a singleton pregnancy of ≥36 gestational weeks. The recruited women were given pre-delivery questionnaires to measure their pain and psychological vulnerabilities. At post-partum 6–10 weeks, an online survey was conducted to collect data on post-partum pain information. Results: Of the 880 recruited women, 816 completed the post-partum pain survey, with 99 (12.1%) having developed SAPC. Giving birth during COVID-19 pandemic (adjusted odds ratio (aOR) 1.64, 95%CI 1.04 to 2.57), greater pre-delivery central sensitization (aOR 1.02, 95%CI 1.00 to 1.04), greater number of pain relief administered (aOR 1.49, 95%CI 1.18 to 1.89), having had artificial rupture of membrane and oxytocic during labor onset (aOR 3.00, 95%CI 1.66 to 5.40), greater volume of blood loss during delivery (every 100 ml; aOR 1.27, 95%CI 1.11 to 1.44), having had third-degree tear during delivery (aOR 4.40, 95%CI 1.33 to 14.51), and greater infant height (aOR 1.14, 95%CI 1.01 to 1.30) were independently associated with greater risk of SAPC. Having greater general health score was protective against the risk of SAPC (aOR 0.99, 95% CI 0.97 to 0.999) (Area under the curve (AUC) = 0.74). Conclusions: The generated multivariable association model may help us better understand the shift in pain and psychological aspects of women during COVID-19 pandemic. |
| first_indexed | 2024-04-24T13:50:32Z |
| format | Article |
| id | doaj.art-881428361d334de8bbd9bf55940b226a |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-24T13:50:32Z |
| publishDate | 2024-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-881428361d334de8bbd9bf55940b226a2024-04-04T05:04:29ZengElsevierHeliyon2405-84402024-03-01106e27240Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trialChin Wen Tan0Rehena Sultana1Azriel Nicol Chang2Hon Sen Tan3Ban Leong Sng4Department of Women's Anesthesia, KK Women's and Children's Hospital, Singapore; Anesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, SingaporeCentre for Quantitative Medicine, Duke-NUS Medical School, SingaporeDuke-NUS Medical School, SingaporeDepartment of Women's Anesthesia, KK Women's and Children's Hospital, Singapore; Anesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, SingaporeDepartment of Women's Anesthesia, KK Women's and Children's Hospital, Singapore; Anesthesiology and Perioperative Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore; Corresponding author. Department of Women's Anesthesia, KK Women's and Children's Hospital, Singapore.Background: COVID-19 pandemic could bring great impact upon the psychological statuses of post-partum women, but no clear evidence was provided yet as to COVID-19 would also affect their pain profile during post-partum period. We determined if pain and psychological vulnerabilities, obstetric factors, and labor analgesia were associated with sub-acute pain after childbirth (SAPC; ongoing pain related to delivery at post-partum 4 weeks or more) during COVID-19 pandemic. Methods: We included women having a singleton pregnancy of ≥36 gestational weeks. The recruited women were given pre-delivery questionnaires to measure their pain and psychological vulnerabilities. At post-partum 6–10 weeks, an online survey was conducted to collect data on post-partum pain information. Results: Of the 880 recruited women, 816 completed the post-partum pain survey, with 99 (12.1%) having developed SAPC. Giving birth during COVID-19 pandemic (adjusted odds ratio (aOR) 1.64, 95%CI 1.04 to 2.57), greater pre-delivery central sensitization (aOR 1.02, 95%CI 1.00 to 1.04), greater number of pain relief administered (aOR 1.49, 95%CI 1.18 to 1.89), having had artificial rupture of membrane and oxytocic during labor onset (aOR 3.00, 95%CI 1.66 to 5.40), greater volume of blood loss during delivery (every 100 ml; aOR 1.27, 95%CI 1.11 to 1.44), having had third-degree tear during delivery (aOR 4.40, 95%CI 1.33 to 14.51), and greater infant height (aOR 1.14, 95%CI 1.01 to 1.30) were independently associated with greater risk of SAPC. Having greater general health score was protective against the risk of SAPC (aOR 0.99, 95% CI 0.97 to 0.999) (Area under the curve (AUC) = 0.74). Conclusions: The generated multivariable association model may help us better understand the shift in pain and psychological aspects of women during COVID-19 pandemic.http://www.sciencedirect.com/science/article/pii/S2405844024032717 |
| spellingShingle | Chin Wen Tan Rehena Sultana Azriel Nicol Chang Hon Sen Tan Ban Leong Sng Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial Heliyon |
| title | Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial |
| title_full | Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial |
| title_fullStr | Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial |
| title_full_unstemmed | Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial |
| title_short | Sub-acute pain after childbirth during COVID-19 pandemic: A secondary analysis of A prospective clinical trial |
| title_sort | sub acute pain after childbirth during covid 19 pandemic a secondary analysis of a prospective clinical trial |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024032717 |
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