Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review
Cardiovascular diseases (CVDs) are recognized as one of the major causes of morbidity and mortality worldwide. Generally, most CVDs can be prevented by addressing behavioral risk factors, including smoking, unhealthy diet and obesity, lack of physical activity, and alcohol abuse. Therefore, it is im...
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| Format: | Article |
| Language: | English |
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IMR Press
2022-04-01
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| Series: | Reviews in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305161 |
| _version_ | 1818470037541879808 |
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| author | Hun-Young Park Sung-Woo Kim Won-Sang Jung Jisu Kim Kiwon Lim |
| author_facet | Hun-Young Park Sung-Woo Kim Won-Sang Jung Jisu Kim Kiwon Lim |
| author_sort | Hun-Young Park |
| collection | DOAJ |
| description | Cardiovascular diseases (CVDs) are recognized as one of the major causes of morbidity and mortality worldwide. Generally, most CVDs can be prevented by addressing behavioral risk factors, including smoking, unhealthy diet and obesity, lack of physical activity, and alcohol abuse. Therefore, it is important to have a healthy lifestyle by performing regular physical activity to improve cardiovascular health and diseases. However, a majority of adults worldwide do not meet the minimum recommendations for regular aerobic exercise, and overweight and obesity ratio continues to rise. In addition, obese individuals, with a high prevalence of CVDs, have a lower participation rate for exercise because of the strain on the musculoskeletal system. Hypoxic therapy, including exposure or exercise intervention under hypoxia, has been utilized as a new therapeutic modality for cardiovascular benefit and amelioration of CVDs. Hypoxic therapy shows various physiological and pathophysiological properties, including increased appetite suppression and dietary intake reduction, increased energy consumption, improved glycogen storage, enhanced fatty acid oxidation, improved myocardial angiogenesis or ventricular remodeling, augmentation of blood flow within the skeletal muscle vascular beds, and reduction of the burden on the musculoskeletal system making it applicable to patients with CVDs and obesity with attenuated cardiovascular function. In particular, hypoxic therapy is very effective in improving cardiovascular benefits and preventing CVDs by enhancing arterial function, vascular endothelial function, and hemorheological properties. These observations indicate that hypoxic therapy may be an important and essential strategy for improving cardiovascular health and reducing cardiovascular morbidity and mortality. |
| first_indexed | 2024-04-13T21:32:29Z |
| format | Article |
| id | doaj.art-8818580989aa49f4ab858ae124d15083 |
| institution | Directory Open Access Journal |
| issn | 1530-6550 |
| language | English |
| last_indexed | 2024-04-13T21:32:29Z |
| publishDate | 2022-04-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Reviews in Cardiovascular Medicine |
| spelling | doaj.art-8818580989aa49f4ab858ae124d150832022-12-22T02:29:07ZengIMR PressReviews in Cardiovascular Medicine1530-65502022-04-0123516110.31083/j.rcm2305161S1530-6550(22)00494-XHypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini ReviewHun-Young Park0Sung-Woo Kim1Won-Sang Jung2Jisu Kim3Kiwon Lim4Department of Sports Medicine and Science, Graduate School, Konkuk University, 05029 Seoul, Republic of KoreaDepartment of Sports Medicine and Science, Graduate School, Konkuk University, 05029 Seoul, Republic of KoreaDepartment of Sports Medicine and Science, Graduate School, Konkuk University, 05029 Seoul, Republic of KoreaDepartment of Sports Medicine and Science, Graduate School, Konkuk University, 05029 Seoul, Republic of KoreaDepartment of Sports Medicine and Science, Graduate School, Konkuk University, 05029 Seoul, Republic of KoreaCardiovascular diseases (CVDs) are recognized as one of the major causes of morbidity and mortality worldwide. Generally, most CVDs can be prevented by addressing behavioral risk factors, including smoking, unhealthy diet and obesity, lack of physical activity, and alcohol abuse. Therefore, it is important to have a healthy lifestyle by performing regular physical activity to improve cardiovascular health and diseases. However, a majority of adults worldwide do not meet the minimum recommendations for regular aerobic exercise, and overweight and obesity ratio continues to rise. In addition, obese individuals, with a high prevalence of CVDs, have a lower participation rate for exercise because of the strain on the musculoskeletal system. Hypoxic therapy, including exposure or exercise intervention under hypoxia, has been utilized as a new therapeutic modality for cardiovascular benefit and amelioration of CVDs. Hypoxic therapy shows various physiological and pathophysiological properties, including increased appetite suppression and dietary intake reduction, increased energy consumption, improved glycogen storage, enhanced fatty acid oxidation, improved myocardial angiogenesis or ventricular remodeling, augmentation of blood flow within the skeletal muscle vascular beds, and reduction of the burden on the musculoskeletal system making it applicable to patients with CVDs and obesity with attenuated cardiovascular function. In particular, hypoxic therapy is very effective in improving cardiovascular benefits and preventing CVDs by enhancing arterial function, vascular endothelial function, and hemorheological properties. These observations indicate that hypoxic therapy may be an important and essential strategy for improving cardiovascular health and reducing cardiovascular morbidity and mortality.https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305161cardiovascular diseasescardiovascular healthhypoxic therapyhypoxic exposurehypoxic training |
| spellingShingle | Hun-Young Park Sung-Woo Kim Won-Sang Jung Jisu Kim Kiwon Lim Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review Reviews in Cardiovascular Medicine cardiovascular diseases cardiovascular health hypoxic therapy hypoxic exposure hypoxic training |
| title | Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review |
| title_full | Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review |
| title_fullStr | Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review |
| title_full_unstemmed | Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review |
| title_short | Hypoxic Therapy as a New Therapeutic Modality for Cardiovascular Benefit: A Mini Review |
| title_sort | hypoxic therapy as a new therapeutic modality for cardiovascular benefit a mini review |
| topic | cardiovascular diseases cardiovascular health hypoxic therapy hypoxic exposure hypoxic training |
| url | https://www.imrpress.com/journal/RCM/23/5/10.31083/j.rcm2305161 |
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