Pathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation

Pathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Hijacks GTPase-Activated p21-Activated Kinase for Actin Pedestal Formation

ABSTRACT Enteropathogenic Escherichia coli and enterohemorrhagic E. coli (EPEC and EHEC, respectively) are extracellular pathogens that reorganize the host cell cytoskeleton to form “actin pedestals” beneath the tightly adherent bacteria, a critical step in pathogenesis. EPEC and EHEC inject effecto...

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Bibliographic Details
Main Authors: Vikash Singh, Anthony Davidson, Peter J. Hume, Vassilis Koronakis
Format: Article
Language:English
Published: American Society for Microbiology 2019-08-01
Series:mBio
Subjects:
actin
EPEC
EspG
GTPases
p21-activated kinases
Online Access:https://journals.asm.org/doi/10.1128/mBio.01876-19

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