Utility of I-SceI and CCR5-ZFN nucleases in excising selectable marker genes from transgenic plants

Utility of I-SceI and CCR5-ZFN nucleases in excising selectable marker genes from transgenic plants

Abstract Objectives Removal of selection marker genes from transgenic plants is highly desirable for their regulatory approval and public acceptance. This study evaluated the use of two nucleases, the yeast homing endonuclease, I-SceI, and the designed zinc finger nuclease, CCR5-ZFN, in excising mar...

Full description

Bibliographic Details
Main Authors: Bhuvan P. Pathak, Eliott Pruett, Huazhong Guan, Vibha Srivastava
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Research Notes
Subjects:
Meganuclease
I-SceI
Zinc finger nuclease
Targeted excision
Genetic engineering
Online Access:http://link.springer.com/article/10.1186/s13104-019-4304-2

Similar Items

Similar Items