Influence of Systemic Therapy on the Expression and Activity of Selected STAT Proteins in Prostate Cancer Tissue

Influence of Systemic Therapy on the Expression and Activity of Selected STAT Proteins in Prostate Cancer Tissue

Signal Transducer and Activator of Transcription (STAT) proteins have been identified as drivers of prostate cancer (PCa) progression and development of aggressive castration-resistant phenotypes. In particular, STAT3, 5, and 6 have been linked to resistance to androgen receptor inhibition and metas...

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Bibliographic Details
Main Authors: Celina Ebersbach, Alicia-Marie K. Beier, Pia Hönscheid, Christian Sperling, Korinna Jöhrens, Gustavo B. Baretton, Christian Thomas, Ulrich Sommer, Angelika Borkowetz, Holger H. H. Erb
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Life
Subjects:
STAT3
STAT5
STAT6
androgen deprivation therapy
novel hormonal therapy
chemotherapy
Online Access:https://www.mdpi.com/2075-1729/12/2/240

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