The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole
With the purpose of research of clinical efficiency of trimetazidine and atenolol and their influence on morfofunctional parameteres of left ventricle 36 men who have transferred a myocardial infarction are inspected. Patients were randomly divided into 2 groups. Clinical status and function state o...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2002-03-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3849 |
| _version_ | 1797873387461148672 |
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| author | V. V. Kalyuzhin M. A. Solovtsov D. U. Kamaev |
| author_facet | V. V. Kalyuzhin M. A. Solovtsov D. U. Kamaev |
| author_sort | V. V. Kalyuzhin |
| collection | DOAJ |
| description | With the purpose of research of clinical efficiency of trimetazidine and atenolol and their influence on morfofunctional parameteres of left ventricle 36 men who have transferred a myocardial infarction are inspected. Patients were randomly divided into 2 groups. Clinical status and function state of left ventricle (by echocardiography) was assessed before and after 4-week therapy with trimetazidine or atenolol. Atenolol and trimetazidine have shown in our study identical clinical efficiency. However while atenolol is statistically significant reduced systolic arterial pressure and heart rate, thickness of posterior wall of left ventricle and corrects diastolic function, trimetazidine had no such activity. Treatment with trimetazidine promoted improvement of local contractility of left ventricle. |
| first_indexed | 2024-04-10T01:15:23Z |
| format | Article |
| id | doaj.art-8820cda35b1c44a4b65c1be6b456e900 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:15:23Z |
| publishDate | 2002-03-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-8820cda35b1c44a4b65c1be6b456e9002023-03-13T09:58:00ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842002-03-0111404410.20538/1682-0363-2002-1-40-442456The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenololeV. V. Kalyuzhin0M. A. Solovtsov1D. U. Kamaev2Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетWith the purpose of research of clinical efficiency of trimetazidine and atenolol and their influence on morfofunctional parameteres of left ventricle 36 men who have transferred a myocardial infarction are inspected. Patients were randomly divided into 2 groups. Clinical status and function state of left ventricle (by echocardiography) was assessed before and after 4-week therapy with trimetazidine or atenolol. Atenolol and trimetazidine have shown in our study identical clinical efficiency. However while atenolol is statistically significant reduced systolic arterial pressure and heart rate, thickness of posterior wall of left ventricle and corrects diastolic function, trimetazidine had no such activity. Treatment with trimetazidine promoted improvement of local contractility of left ventricle.https://bulletin.ssmu.ru/jour/article/view/3849ишемическая дисфункция миокардалечениетриметазидинатенолол |
| spellingShingle | V. V. Kalyuzhin M. A. Solovtsov D. U. Kamaev The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole Бюллетень сибирской медицины ишемическая дисфункция миокарда лечение триметазидин атенолол |
| title | The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole |
| title_full | The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole |
| title_fullStr | The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole |
| title_full_unstemmed | The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole |
| title_short | The effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle: the results of the randomization research of trimetazidine and athenolole |
| title_sort | effectiveness of cytocardioprotection of patients with the moderately expressed post infarct dysfunction of left heart ventricle the results of the randomization research of trimetazidine and athenolole |
| topic | ишемическая дисфункция миокарда лечение триметазидин атенолол |
| url | https://bulletin.ssmu.ru/jour/article/view/3849 |
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