Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation

Renal lymphoma occurs most often as a part of a multi-systemic disseminated lymphoma or as a recurrence of the tumor. Renal involvement usually occurs late in the course of the disease and is clinically silent. Acute renal failure (ARF) from lymphomatous infiltration has been described but is quite...

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Main Authors: Harzallah Kais, Laadidi Jannet, Chatti Kais, Hlel Imed, Bougrine Fethi, Bouziani Ammar, Abdallah Nejib, Louzir Bassam, Othmani Salah, Boussema Ezzedine
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2006-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Subjects:
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2006;volume=17;issue=3;spage=395;epage=398;aulast=Harzallah
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author Harzallah Kais
Laadidi Jannet
Chatti Kais
Hlel Imed
Bougrine Fethi
Bouziani Ammar
Abdallah Nejib
Louzir Bassam
Othmani Salah
Boussema Ezzedine
author_facet Harzallah Kais
Laadidi Jannet
Chatti Kais
Hlel Imed
Bougrine Fethi
Bouziani Ammar
Abdallah Nejib
Louzir Bassam
Othmani Salah
Boussema Ezzedine
author_sort Harzallah Kais
collection DOAJ
description Renal lymphoma occurs most often as a part of a multi-systemic disseminated lymphoma or as a recurrence of the tumor. Renal involvement usually occurs late in the course of the disease and is clinically silent. Acute renal failure (ARF) from lymphomatous infiltration has been described but is quite rare. We report a 50-year-old Caucasian woman, who presented with features of ARF. Physical examination showed that her arterial blood pressure was 190/100 mm Hg with no lymphadenopathy or hepatosplenomegaly. Her urine output was about 100 ml/day, and urinanalysis revealed + proteinuria and microscopic hematuria. Biochemical findings revealed severely impaired renal function with a serum creatinine of 693 µmol/L. The patient′s lactate dehydrogenase was elevated at 632 U/L. An abdominal ultrasound showed bilateral, large non-obstructed kidneys and a hypoechoic mass arising in the right lobe of the liver. An ultrasound-guided percutaneous liver biopsy showed typical features of B-cell lymphoblastic lymphoma. The patient expired two days later, even before any specific treatment could be started.
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spelling doaj.art-88293139de47421cbba02dcb06a97b192022-12-22T00:49:24ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422006-01-01173395398Acute Renal Failure due to Lymphomatous Infiltration: An Unusual PresentationHarzallah KaisLaadidi JannetChatti KaisHlel ImedBougrine FethiBouziani AmmarAbdallah NejibLouzir BassamOthmani SalahBoussema EzzedineRenal lymphoma occurs most often as a part of a multi-systemic disseminated lymphoma or as a recurrence of the tumor. Renal involvement usually occurs late in the course of the disease and is clinically silent. Acute renal failure (ARF) from lymphomatous infiltration has been described but is quite rare. We report a 50-year-old Caucasian woman, who presented with features of ARF. Physical examination showed that her arterial blood pressure was 190/100 mm Hg with no lymphadenopathy or hepatosplenomegaly. Her urine output was about 100 ml/day, and urinanalysis revealed + proteinuria and microscopic hematuria. Biochemical findings revealed severely impaired renal function with a serum creatinine of 693 µmol/L. The patient′s lactate dehydrogenase was elevated at 632 U/L. An abdominal ultrasound showed bilateral, large non-obstructed kidneys and a hypoechoic mass arising in the right lobe of the liver. An ultrasound-guided percutaneous liver biopsy showed typical features of B-cell lymphoblastic lymphoma. The patient expired two days later, even before any specific treatment could be started.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2006;volume=17;issue=3;spage=395;epage=398;aulast=HarzallahLymphomaAcute renal failureIntrarenal infiltration.
spellingShingle Harzallah Kais
Laadidi Jannet
Chatti Kais
Hlel Imed
Bougrine Fethi
Bouziani Ammar
Abdallah Nejib
Louzir Bassam
Othmani Salah
Boussema Ezzedine
Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
Saudi Journal of Kidney Diseases and Transplantation
Lymphoma
Acute renal failure
Intrarenal infiltration.
title Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
title_full Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
title_fullStr Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
title_full_unstemmed Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
title_short Acute Renal Failure due to Lymphomatous Infiltration: An Unusual Presentation
title_sort acute renal failure due to lymphomatous infiltration an unusual presentation
topic Lymphoma
Acute renal failure
Intrarenal infiltration.
url http://www.sjkdt.org/article.asp?issn=1319-2442;year=2006;volume=17;issue=3;spage=395;epage=398;aulast=Harzallah
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