Spindle Cell Carcinoma of the hypopharynx: a case report

<p>Spindle cell carcinoma of hpopharynx is a rare pathology. It is a poorly differentiated variant of squamous cell carcinoma and morphologically resembles sarcoma. This is a disease of old age. It is usually associated with smoking and alcohol abuse. When it is associated with radiation expos...

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Main Author: Dillu Ram Kandel
Format: Article
Language:English
Published: College of Medical Sciences 2018-03-01
Series:Journal of College of Medical Sciences-Nepal
Subjects:
Online Access:https://www.nepjol.info/index.php/JCMSN/article/view/19241
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author Dillu Ram Kandel
author_facet Dillu Ram Kandel
author_sort Dillu Ram Kandel
collection DOAJ
description <p>Spindle cell carcinoma of hpopharynx is a rare pathology. It is a poorly differentiated variant of squamous cell carcinoma and morphologically resembles sarcoma. This is a disease of old age. It is usually associated with smoking and alcohol abuse. When it is associated with radiation exposure history it behaves more aggressively. Surgery is considered as the main modality of treatment and adjuvant radiotherapy if necessary. Here we present a case of 79 year old male with spindle cell carcinomaof right piriform fossa with 2-month history of progressive dysphasia and hoarseness that has been affecting his ability to speak and swallow with history of weight loss and past history of radiotherapy. So possibility of spindle cell carcinoma of the hypopharynx should beconsidered in an old patient with rapidly developing swelling of the hypopharynx with past history of radiation exposure. As it is a highly aggressive disease it should be treated timely and more aggressively to prolong the survival of the patient.</p><p> </p><p> </p><p> </p>
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spelling doaj.art-882f7bd5462d4225b43a6ef7568f3a742022-12-21T19:28:08ZengCollege of Medical SciencesJournal of College of Medical Sciences-Nepal2091-06572091-06732018-03-01141596110.3126/jcmsn.v14i1.1924115131Spindle Cell Carcinoma of the hypopharynx: a case reportDillu Ram Kandel0BPKIHS<p>Spindle cell carcinoma of hpopharynx is a rare pathology. It is a poorly differentiated variant of squamous cell carcinoma and morphologically resembles sarcoma. This is a disease of old age. It is usually associated with smoking and alcohol abuse. When it is associated with radiation exposure history it behaves more aggressively. Surgery is considered as the main modality of treatment and adjuvant radiotherapy if necessary. Here we present a case of 79 year old male with spindle cell carcinomaof right piriform fossa with 2-month history of progressive dysphasia and hoarseness that has been affecting his ability to speak and swallow with history of weight loss and past history of radiotherapy. So possibility of spindle cell carcinoma of the hypopharynx should beconsidered in an old patient with rapidly developing swelling of the hypopharynx with past history of radiation exposure. As it is a highly aggressive disease it should be treated timely and more aggressively to prolong the survival of the patient.</p><p> </p><p> </p><p> </p>https://www.nepjol.info/index.php/JCMSN/article/view/19241Spindle cell carcinomapiriform fossaradiotherapy
spellingShingle Dillu Ram Kandel
Spindle Cell Carcinoma of the hypopharynx: a case report
Journal of College of Medical Sciences-Nepal
Spindle cell carcinoma
piriform fossa
radiotherapy
title Spindle Cell Carcinoma of the hypopharynx: a case report
title_full Spindle Cell Carcinoma of the hypopharynx: a case report
title_fullStr Spindle Cell Carcinoma of the hypopharynx: a case report
title_full_unstemmed Spindle Cell Carcinoma of the hypopharynx: a case report
title_short Spindle Cell Carcinoma of the hypopharynx: a case report
title_sort spindle cell carcinoma of the hypopharynx a case report
topic Spindle cell carcinoma
piriform fossa
radiotherapy
url https://www.nepjol.info/index.php/JCMSN/article/view/19241
work_keys_str_mv AT dilluramkandel spindlecellcarcinomaofthehypopharynxacasereport