Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway

Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway

Abstract Background Glucuronic acid metabolism participates in cellular detoxification, extracellular matrix remodeling and cell adhesion and migration. Here, we aimed to explore the crosstalk between dysregulated glucuronic acid metabolism and crucial metastatic signalling in glutathione S‐transfer...

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Bibliographic Details
Main Authors: Qingzhu Gao, Bin Cheng, Chang Chen, Chong Lei, Xue Lin, Dan Nie, Jingjing Li, Luyi Huang, Xiaosong Li, Kai Wang, Ailong Huang, Ni Tang
Format: Article
Language:English
Published: Wiley 2022-08-01
Series:Clinical and Translational Medicine
Subjects:
hepatocellular carcinoma metastasis
TGFβ/Smad signalling
UDP‐GlcUA
UGDH
Online Access:https://doi.org/10.1002/ctm2.995

Internet

https://doi.org/10.1002/ctm2.995

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