Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease
AIM: To study the impact of low-intensity laser irradiation on 24-hour pH-metry parameters and prostaglandin E2 (PGE2) levels in patients with gastroesophageal reflux disease (GERD). /MATERIAL AND METHODS: One hundred and twelve patients aged 19 to 79 years with GERD were examined. Seventy-eight pat...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2012-12-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31158 |
| Summary: | AIM: To study the impact of low-intensity laser irradiation on 24-hour pH-metry parameters and prostaglandin E2 (PGE2) levels in patients with gastroesophageal reflux disease (GERD). /MATERIAL AND METHODS: One hundred and twelve patients aged 19 to 79 years with GERD were examined. Seventy-eight patients received a 10-day course of continuous intravenous laser therapy using a Matrix VLOK laser therapy apparatus (Matrix, Russia) with a wavelength of 0.405 µm, radiation power at the exit of a main light guide 1-1.5 mW, pulse rate 80 Hz. The indicators under study were determined before and after treatment /RESULTS: After treatment, the intravenous laser therapy group showed a significant increase in PGE2 (1376±93 pg/ml) to the levels typical of those in healthy individuals and a significant decrease in all esophageal pH-metry parameters; the DeMeester score achieved normal values, and all quality of life (QL) indicators, except for physical function index, significantly improved (10.2±5.7; р |
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| ISSN: | 0040-3660 2309-5342 |