Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease
AIM: To study the impact of low-intensity laser irradiation on 24-hour pH-metry parameters and prostaglandin E2 (PGE2) levels in patients with gastroesophageal reflux disease (GERD). /MATERIAL AND METHODS: One hundred and twelve patients aged 19 to 79 years with GERD were examined. Seventy-eight pat...
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| Format: | Article |
| Language: | Russian |
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"Consilium Medicum" Publishing house
2012-12-01
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| Series: | Терапевтический архив |
| Subjects: | |
| Online Access: | https://ter-arkhiv.ru/0040-3660/article/view/31158 |
| _version_ | 1818684421757206528 |
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| author | N M Burduli D Ia Tadtaeva |
| author_facet | N M Burduli D Ia Tadtaeva |
| author_sort | N M Burduli |
| collection | DOAJ |
| description | AIM: To study the impact of low-intensity laser irradiation on 24-hour pH-metry parameters and prostaglandin E2 (PGE2) levels in patients with gastroesophageal reflux disease (GERD). /MATERIAL AND METHODS: One hundred and twelve patients aged 19 to 79 years with GERD were examined. Seventy-eight patients received a 10-day course of continuous intravenous laser therapy using a Matrix VLOK laser therapy apparatus (Matrix, Russia) with a wavelength of 0.405 µm, radiation power at the exit of a main light guide 1-1.5 mW, pulse rate 80 Hz. The indicators under study were determined before and after treatment /RESULTS: After treatment, the intravenous laser therapy group showed a significant increase in PGE2 (1376±93 pg/ml) to the levels typical of those in healthy individuals and a significant decrease in all esophageal pH-metry parameters; the DeMeester score achieved normal values, and all quality of life (QL) indicators, except for physical function index, significantly improved (10.2±5.7; р |
| first_indexed | 2024-12-17T10:50:22Z |
| format | Article |
| id | doaj.art-883380a2aa8349cc88dbcb4063faef5a |
| institution | Directory Open Access Journal |
| issn | 0040-3660 2309-5342 |
| language | Russian |
| last_indexed | 2024-12-17T10:50:22Z |
| publishDate | 2012-12-01 |
| publisher | "Consilium Medicum" Publishing house |
| record_format | Article |
| series | Терапевтический архив |
| spelling | doaj.art-883380a2aa8349cc88dbcb4063faef5a2022-12-21T21:52:00Zrus"Consilium Medicum" Publishing houseТерапевтический архив0040-36602309-53422012-12-018412586128174Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux diseaseN M BurduliD Ia TadtaevaAIM: To study the impact of low-intensity laser irradiation on 24-hour pH-metry parameters and prostaglandin E2 (PGE2) levels in patients with gastroesophageal reflux disease (GERD). /MATERIAL AND METHODS: One hundred and twelve patients aged 19 to 79 years with GERD were examined. Seventy-eight patients received a 10-day course of continuous intravenous laser therapy using a Matrix VLOK laser therapy apparatus (Matrix, Russia) with a wavelength of 0.405 µm, radiation power at the exit of a main light guide 1-1.5 mW, pulse rate 80 Hz. The indicators under study were determined before and after treatment /RESULTS: After treatment, the intravenous laser therapy group showed a significant increase in PGE2 (1376±93 pg/ml) to the levels typical of those in healthy individuals and a significant decrease in all esophageal pH-metry parameters; the DeMeester score achieved normal values, and all quality of life (QL) indicators, except for physical function index, significantly improved (10.2±5.7; рhttps://ter-arkhiv.ru/0040-3660/article/view/31158gastroesophageal reflux disease24-hour ph-metryprostaglandin e2laser therapy |
| spellingShingle | N M Burduli D Ia Tadtaeva Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease Терапевтический архив gastroesophageal reflux disease 24-hour ph-metry prostaglandin e2 laser therapy |
| title | Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease |
| title_full | Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease |
| title_fullStr | Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease |
| title_full_unstemmed | Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease |
| title_short | Impact of laser therapy on PGE2 level, 24-hour pH-metry changes, and quality of life in patients with gastroesophageal reflux disease |
| title_sort | impact of laser therapy on pge2 level 24 hour ph metry changes and quality of life in patients with gastroesophageal reflux disease |
| topic | gastroesophageal reflux disease 24-hour ph-metry prostaglandin e2 laser therapy |
| url | https://ter-arkhiv.ru/0040-3660/article/view/31158 |
| work_keys_str_mv | AT nmburduli impactoflasertherapyonpge2level24hourphmetrychangesandqualityoflifeinpatientswithgastroesophagealrefluxdisease AT diatadtaeva impactoflasertherapyonpge2level24hourphmetrychangesandqualityoflifeinpatientswithgastroesophagealrefluxdisease |