Experimental validation of a bias in apparent exchange rate measurement

Double diffusion encoding (DDE) MRI is a technique in which two diffusion weighted periods are applied between excitation and acquisition. This allows to acquire structural information (as pore size and shape) and molecular exchange between compartments, in terms of apparent exchange rate (AXR). How...

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Main Authors: Ulloa Patricia, Methot Vincent, Koch Martin A.
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2017-0112
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author Ulloa Patricia
Methot Vincent
Koch Martin A.
author_facet Ulloa Patricia
Methot Vincent
Koch Martin A.
author_sort Ulloa Patricia
collection DOAJ
description Double diffusion encoding (DDE) MRI is a technique in which two diffusion weighted periods are applied between excitation and acquisition. This allows to acquire structural information (as pore size and shape) and molecular exchange between compartments, in terms of apparent exchange rate (AXR). However, it has not been well investigated yet whether the diffusion restriction underlying DDE size estimation may compromise AXR results.
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spelling doaj.art-88339f023f3f4efea50591293e9291ac2023-04-11T17:07:14ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042017-09-013252953210.1515/cdbme-2017-0112cdbme-2017-0112Experimental validation of a bias in apparent exchange rate measurementUlloa Patricia0Methot Vincent1Koch Martin A.2Institute of Medical Engineering. University of Luebeck. Ratzeburger Allee 160. 23562 Luebeck, GermanyInstitute of Medical Engineering. University of Luebeck. Ratzeburger Allee 160. 23562 Luebeck, GermanyInstitute of Medical Engineering. University of Luebeck. Ratzeburger Allee 160. 23562 Luebeck, GermanyDouble diffusion encoding (DDE) MRI is a technique in which two diffusion weighted periods are applied between excitation and acquisition. This allows to acquire structural information (as pore size and shape) and molecular exchange between compartments, in terms of apparent exchange rate (AXR). However, it has not been well investigated yet whether the diffusion restriction underlying DDE size estimation may compromise AXR results.https://doi.org/10.1515/cdbme-2017-0112double diffusion encoding (dde)apparent exchange ratewater-in-oil emulsion
spellingShingle Ulloa Patricia
Methot Vincent
Koch Martin A.
Experimental validation of a bias in apparent exchange rate measurement
Current Directions in Biomedical Engineering
double diffusion encoding (dde)
apparent exchange rate
water-in-oil emulsion
title Experimental validation of a bias in apparent exchange rate measurement
title_full Experimental validation of a bias in apparent exchange rate measurement
title_fullStr Experimental validation of a bias in apparent exchange rate measurement
title_full_unstemmed Experimental validation of a bias in apparent exchange rate measurement
title_short Experimental validation of a bias in apparent exchange rate measurement
title_sort experimental validation of a bias in apparent exchange rate measurement
topic double diffusion encoding (dde)
apparent exchange rate
water-in-oil emulsion
url https://doi.org/10.1515/cdbme-2017-0112
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AT methotvincent experimentalvalidationofabiasinapparentexchangeratemeasurement
AT kochmartina experimentalvalidationofabiasinapparentexchangeratemeasurement