Anti-Septic Functions of Cornuside against HMGB1-Mediated Severe Inflammatory Responses

High mobility group box 1 (HMGB1) is acknowledged to have critical functions; therefore, targeting this protein may have therapeutic effects. One example is potential antiseptic activity obtained by suppressing HMGB1 secretion, leading to the recovery of vascular barrier integrity. Cornuside (CN), w...

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Bibliographic Details
Main Authors: Nayeon Kim, Chaeyeong Kim, Soo Ho Ryu, Wonhwa Lee, Jong-Sup Bae
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/4/2065