Cadmium facilitates the formation of large lipid droplets via PLCβ2-DAG-DGKε-PA signal pathway in Leydig cells

Cadmium facilitates the formation of large lipid droplets via PLCβ2-DAG-DGKε-PA signal pathway in Leydig cells

Cadmium (Cd) exposure damages the reproductive system. Lipid droplets (LDs) play an important role in steroid-producing cells to provide raw material for steroid hormone. We have found that the LDs of Leydig cells exposed to Cd are bigger than those of normal cells, but the effects on steroidogenesi...

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Bibliographic Details
Main Authors: Youjin Wang, Yuqing Liang, Zansheng Yuan, Wanwen Mai, Yang Leng, Runze Zhang, Jiayan Chen, Caiyong Lai, Hongxia Chen, Xiaoping Wu, Chao Sheng, Qihao Zhang
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Cadmium
Lipid droplets
PLCβ2
Phosphatidic acid
Leydig cells
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323011144

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