Early life stress dysregulates kappa opioid receptor signaling within the lateral habenula

The lateral habenula (LHb) is an epithalamic brain region associated with value-based decision making and stress evasion through its modulation of dopamine (DA)-mediated reward circuitry. Specifically, increased activity of the LHb is associated with drug addiction, schizophrenia and stress-related...

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Bibliographic Details
Main Authors: Sarah C. Simmons, Ryan D. Shepard, Shawn Gouty, Ludovic D. Langlois, William J. Flerlage, Brian M. Cox, Fereshteh S. Nugent
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352289520300576