Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas

Objective. To investigate the efficacy of immunomodulating and immunostimulating therapy in complex treatment of patients, suffering surgical forms of erysipelas.Materials and methods. Retrospectively and prospectively there were analyzed 284 patients’ hospital charts, who were treated stationary in...

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Main Authors: S. D. Shapoval, L. L. Vorontsova, L. A. Vasylevska
Format: Article
Language:Russian
Published: Liga-Inform ltd. 2021-10-01
Series:Клінічна хірургія
Subjects:
Online Access:https://hirurgiya.com.ua/index.php/journal/article/view/941
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author S. D. Shapoval
L. L. Vorontsova
L. A. Vasylevska
author_facet S. D. Shapoval
L. L. Vorontsova
L. A. Vasylevska
author_sort S. D. Shapoval
collection DOAJ
description Objective. To investigate the efficacy of immunomodulating and immunostimulating therapy in complex treatment of patients, suffering surgical forms of erysipelas.Materials and methods. Retrospectively and prospectively there were analyzed 284 patients’ hospital charts, who were treated stationary in Centre of Purulent-Septic Surgery of Zaporizhzhya Municipal Hospital №3 in 2016 - 2021 yrs. Results. In patients, suffering erythematous form of erysipelas, disorders in cellular and humoral chains of immunity were not revealed. The immune disorders formula in bullous form was following: CD3 + 1, CD4 + 1, CD8-1, CD16-2, CD22-1, what witnessed about misbalance of the immune system Degree I, of possibly compensatory character; in a phlegmonous one - CD3 + 1, CD4-1, CD8-1, CD16-2, CD22-1, witnessing actuality of the immune disorders of Degree І, while in the necrotic one - CD3-2, CD4-2, CD8-1, CD16-2, CD22-1, trusting presence of the immune disorders of Degree ІІI. Conclusion. Administration of erbisol-extra and laferon for destructive forms of erysipelas is pathogenetically substantiated and may be applied in complex treatment of the disease.
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spelling doaj.art-884e085e7eab479d90f74fbfaa1a987d2023-04-25T13:54:15ZrusLiga-Inform ltd.Клінічна хірургія0023-21302522-13962021-10-01885-6535510.26779/2522-1396.2021.5-6.53941Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelasS. D. Shapoval0L. L. Vorontsova1L. A. Vasylevska2Zaporizhzhya Medical Academy of Post-Graduate EducationZaporizhzhya Medical Academy of Post-Graduate EducationZaporizhzhya Medical Academy of Post-Graduate EducationObjective. To investigate the efficacy of immunomodulating and immunostimulating therapy in complex treatment of patients, suffering surgical forms of erysipelas.Materials and methods. Retrospectively and prospectively there were analyzed 284 patients’ hospital charts, who were treated stationary in Centre of Purulent-Septic Surgery of Zaporizhzhya Municipal Hospital №3 in 2016 - 2021 yrs. Results. In patients, suffering erythematous form of erysipelas, disorders in cellular and humoral chains of immunity were not revealed. The immune disorders formula in bullous form was following: CD3 + 1, CD4 + 1, CD8-1, CD16-2, CD22-1, what witnessed about misbalance of the immune system Degree I, of possibly compensatory character; in a phlegmonous one - CD3 + 1, CD4-1, CD8-1, CD16-2, CD22-1, witnessing actuality of the immune disorders of Degree І, while in the necrotic one - CD3-2, CD4-2, CD8-1, CD16-2, CD22-1, trusting presence of the immune disorders of Degree ІІI. Conclusion. Administration of erbisol-extra and laferon for destructive forms of erysipelas is pathogenetically substantiated and may be applied in complex treatment of the disease.https://hirurgiya.com.ua/index.php/journal/article/view/941surgical forms of erysipelas; іmmunomodulating therapy; іmmunostimulating therapy.
spellingShingle S. D. Shapoval
L. L. Vorontsova
L. A. Vasylevska
Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
Клінічна хірургія
surgical forms of erysipelas; іmmunomodulating therapy; іmmunostimulating therapy.
title Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
title_full Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
title_fullStr Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
title_full_unstemmed Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
title_short Application of the immune-correcting therapy in complex treatment of surgical forms of erysipelas
title_sort application of the immune correcting therapy in complex treatment of surgical forms of erysipelas
topic surgical forms of erysipelas; іmmunomodulating therapy; іmmunostimulating therapy.
url https://hirurgiya.com.ua/index.php/journal/article/view/941
work_keys_str_mv AT sdshapoval applicationoftheimmunecorrectingtherapyincomplextreatmentofsurgicalformsoferysipelas
AT llvorontsova applicationoftheimmunecorrectingtherapyincomplextreatmentofsurgicalformsoferysipelas
AT lavasylevska applicationoftheimmunecorrectingtherapyincomplextreatmentofsurgicalformsoferysipelas