Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy
IntroductionLate diagnosis of hydroxychloroquine retinopathy remains a major concern, with the potential for irreversible visual impairment. This study aimed to investigate the causes of late diagnosis in a hospital-based cohort of Korean patients with hydroxychloroquine retinopathy and assess the t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1238226/full |
| _version_ | 1797678167216881664 |
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| author | Seong Joon Ahn Ji Hong Kim |
| author_facet | Seong Joon Ahn Ji Hong Kim |
| author_sort | Seong Joon Ahn |
| collection | DOAJ |
| description | IntroductionLate diagnosis of hydroxychloroquine retinopathy remains a major concern, with the potential for irreversible visual impairment. This study aimed to investigate the causes of late diagnosis in a hospital-based cohort of Korean patients with hydroxychloroquine retinopathy and assess the trend of late diagnosis from 2015 to 2022.MethodsThirty-eight patients with a late diagnosis (severe stage at diagnosis) among 94 patients with hydroxychloroquine retinopathy were included in the analysis. The causes of late diagnosis were categorized as referral-related, patient-related, and screening-related factors.ResultsThe most prevalent cause was no or late referral to ophthalmologists, contributing to a significant gap in timely identification. Patient-related causes included delayed monitoring visits despite scheduled appointments and early-onset disease. Screening-related causes encompassed an insufficient number of sensitive tests, leading to inadequate evidence for diagnosis, and missed or wrong diagnoses by screening physicians. The proportion of late diagnoses decreased over time, indicating improvements in overall screening and detection. The decreasing proportions of screening-related causes suggest advancements in screening practices and the use of multiple sensitive tests for screening.DiscussionEfforts to further reduce late diagnoses and improve screening and diagnostic processes are necessary. Our data emphasize the importance of timely referral to ophthalmologists for early detection and management. |
| first_indexed | 2024-03-11T22:54:47Z |
| format | Article |
| id | doaj.art-8850046252fb454dace798a763ee690f |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-11T22:54:47Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-8850046252fb454dace798a763ee690f2023-09-21T17:21:20ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-09-011010.3389/fmed.2023.12382261238226Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathySeong Joon AhnJi Hong KimIntroductionLate diagnosis of hydroxychloroquine retinopathy remains a major concern, with the potential for irreversible visual impairment. This study aimed to investigate the causes of late diagnosis in a hospital-based cohort of Korean patients with hydroxychloroquine retinopathy and assess the trend of late diagnosis from 2015 to 2022.MethodsThirty-eight patients with a late diagnosis (severe stage at diagnosis) among 94 patients with hydroxychloroquine retinopathy were included in the analysis. The causes of late diagnosis were categorized as referral-related, patient-related, and screening-related factors.ResultsThe most prevalent cause was no or late referral to ophthalmologists, contributing to a significant gap in timely identification. Patient-related causes included delayed monitoring visits despite scheduled appointments and early-onset disease. Screening-related causes encompassed an insufficient number of sensitive tests, leading to inadequate evidence for diagnosis, and missed or wrong diagnoses by screening physicians. The proportion of late diagnoses decreased over time, indicating improvements in overall screening and detection. The decreasing proportions of screening-related causes suggest advancements in screening practices and the use of multiple sensitive tests for screening.DiscussionEfforts to further reduce late diagnoses and improve screening and diagnostic processes are necessary. Our data emphasize the importance of timely referral to ophthalmologists for early detection and management.https://www.frontiersin.org/articles/10.3389/fmed.2023.1238226/fullcausehydroxychloroquine retinopathylate diagnosisreferralscreening |
| spellingShingle | Seong Joon Ahn Ji Hong Kim Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy Frontiers in Medicine cause hydroxychloroquine retinopathy late diagnosis referral screening |
| title | Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy |
| title_full | Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy |
| title_fullStr | Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy |
| title_full_unstemmed | Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy |
| title_short | Causes and trends of late diagnosis in Korean patients with hydroxychloroquine retinopathy |
| title_sort | causes and trends of late diagnosis in korean patients with hydroxychloroquine retinopathy |
| topic | cause hydroxychloroquine retinopathy late diagnosis referral screening |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1238226/full |
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