IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease
Abstract Immunoglobulin G4 (IgG4)‐related disease (IgG4‐RD) is a multi‐organ immune‐mediated fibroinflammatory disorder that may imitate malignancy, infectious or any other inflammatory disorder. IgG4‐related retroperitoneal fibrosis (IgG4‐RPF) is a rare form of IgG4‐RD, diagnosis of which is often...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-09-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7865 |
| _version_ | 1797655182218100736 |
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| author | Saika Farook Md. Shariful Alam Jilani Md. Kamrul Islam Shamima Rahman Rumana Ashraf Naval Mendiratta Sudhir Kumar Rawal |
| author_facet | Saika Farook Md. Shariful Alam Jilani Md. Kamrul Islam Shamima Rahman Rumana Ashraf Naval Mendiratta Sudhir Kumar Rawal |
| author_sort | Saika Farook |
| collection | DOAJ |
| description | Abstract Immunoglobulin G4 (IgG4)‐related disease (IgG4‐RD) is a multi‐organ immune‐mediated fibroinflammatory disorder that may imitate malignancy, infectious or any other inflammatory disorder. IgG4‐related retroperitoneal fibrosis (IgG4‐RPF) is a rare form of IgG4‐RD, diagnosis of which is often relied on radiological technology. Herein, we describe a case of 60 year old male, presenting with low back pain and weight loss for a period of 2 months and 15 days. Imaging studies showed a retroperitoneal tumorous mass along with bilateral hydroureteronephrosis, which was later confirmed to be IgG4‐related retroperitoneal fibrosis on the basis of extensive histopathological analysis. Immunosuppressive therapy resulted in a decrease in fibrosis and restoration of renal function. |
| first_indexed | 2024-03-11T17:10:29Z |
| format | Article |
| id | doaj.art-8854d6b4b85c4799ade5a614d84eb900 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-11T17:10:29Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-8854d6b4b85c4799ade5a614d84eb9002023-10-20T06:16:21ZengWileyClinical Case Reports2050-09042023-09-01119n/an/a10.1002/ccr3.7865IgG4‐related retroperitoneal fibrosis: A case report of a challenging diseaseSaika Farook0Md. Shariful Alam Jilani1Md. Kamrul Islam2Shamima Rahman3Rumana Ashraf4Naval Mendiratta5Sudhir Kumar Rawal6Department of Microbiology Ibrahim Medical College Dhaka BangladeshDepartment of Microbiology Ibrahim Medical College Dhaka BangladeshDepartment of Urology Dhaka Medical College and Hospital & Department of Urology, Centre for Kidney Disease & Hospital Dhaka BangladeshDepartment of Obstetrics and Gynecology, Colonel Malek Medical College and Hospital, Manikganj University of Dhaka Dhaka BangladeshDepartment of Obstetrics and Gynecology Dr. Sirajul Islam Medical College & Hospital Ltd Dhaka BangladeshDepartment of Rheumatology Fortis Memorial Research Institute Gurugram IndiaDepartment of Urogenital Oncology Rajeev Gandhi Cancer Hospital and Research Centre New Delhi IndiaAbstract Immunoglobulin G4 (IgG4)‐related disease (IgG4‐RD) is a multi‐organ immune‐mediated fibroinflammatory disorder that may imitate malignancy, infectious or any other inflammatory disorder. IgG4‐related retroperitoneal fibrosis (IgG4‐RPF) is a rare form of IgG4‐RD, diagnosis of which is often relied on radiological technology. Herein, we describe a case of 60 year old male, presenting with low back pain and weight loss for a period of 2 months and 15 days. Imaging studies showed a retroperitoneal tumorous mass along with bilateral hydroureteronephrosis, which was later confirmed to be IgG4‐related retroperitoneal fibrosis on the basis of extensive histopathological analysis. Immunosuppressive therapy resulted in a decrease in fibrosis and restoration of renal function.https://doi.org/10.1002/ccr3.7865immunoglobulin‐G4‐related disease (IgG4‐RD)retroperitoneal fibrosissystemic disease |
| spellingShingle | Saika Farook Md. Shariful Alam Jilani Md. Kamrul Islam Shamima Rahman Rumana Ashraf Naval Mendiratta Sudhir Kumar Rawal IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease Clinical Case Reports immunoglobulin‐G4‐related disease (IgG4‐RD) retroperitoneal fibrosis systemic disease |
| title | IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease |
| title_full | IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease |
| title_fullStr | IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease |
| title_full_unstemmed | IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease |
| title_short | IgG4‐related retroperitoneal fibrosis: A case report of a challenging disease |
| title_sort | igg4 related retroperitoneal fibrosis a case report of a challenging disease |
| topic | immunoglobulin‐G4‐related disease (IgG4‐RD) retroperitoneal fibrosis systemic disease |
| url | https://doi.org/10.1002/ccr3.7865 |
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