EKSTRAK BAWANG PUTIH (Allium sativum L) SEBAGAI ZAT AKTIF PADA FORMULASI SEDIAAN GEL

Garlic (Allium sativum L) has a nickname as a natural antibiotic. Application of garlic on the face also has several benefits that can cure acne (acne vulgaris). The purpose of this research is to make gel preparation as active substance that is used garlic extract (Allium sativum L). Methods in lab...

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Bibliographic Details
Main Authors: Densi Selpia Sopianti, Putri Serindang Bulan
Format: Article
Language:English
Published: Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin 2018-03-01
Series:JIIS: Jurnal Ilmiah Ibnu Sina
Subjects:
Online Access:http://jiis.akfar-isfibjm.ac.id/index.php/JIIS/article/view/130/119
Description
Summary:Garlic (Allium sativum L) has a nickname as a natural antibiotic. Application of garlic on the face also has several benefits that can cure acne (acne vulgaris). The purpose of this research is to make gel preparation as active substance that is used garlic extract (Allium sativum L). Methods in laboratory experimental research, in which garlic as an active ingredient is extracted using maseration method. Three variants of the preparation formulation were 3%, 5%, and 7% and other additives in gel preparation using Na.CMC, nipagin and nipasol, glycerol and olium guajava. Each gel formula was evaluated for the preparation including organoleptis, homogeneity, pH test, spreading test, and irritation test. The result of evaluation of gel physical properties of the three formulas with variation of garlic extract at different concentrations produced formula I with concentration of garlic extract 3% yielded better test than Formula II and formula III.
ISSN:2502-647X
2503-1902