Thyroglossal cyst malignancy: Two case reports with review of literature

Thyroglossal cyst is formed from the remnant of thyroglossal tract around 8th–10th weeks of gestation. Thyroglossal cyst is the most common congenital mass found in neck midline. Development of carcinoma in thyroglossal cyst is rare, with an incidence of 0.7%–1.0%. Nearly 90% of the malignancies dev...

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Bibliographic Details
Main Author: Shailja Puri
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Journal of Head & Neck Physicians and Surgeons
Subjects:
Online Access:http://www.jhnps.org/article.asp?issn=2347-8128;year=2017;volume=5;issue=2;spage=82;epage=85;aulast=Puri
Description
Summary:Thyroglossal cyst is formed from the remnant of thyroglossal tract around 8th–10th weeks of gestation. Thyroglossal cyst is the most common congenital mass found in neck midline. Development of carcinoma in thyroglossal cyst is rare, with an incidence of 0.7%–1.0%. Nearly 90% of the malignancies developing in thyroglossal cyst are thyrogenic in origin arising from the ectopic thyroid tissue. Squamous cell carcinoma accounts for <1% of all thyroglossal cyst malignancies. Thyroglossal cyst carcinomas of thyrogenic origin are managed with Sistrunk procedure along with thyroidectomy. Thyroidectomy is recommended because thyroid carcinomas, especially papillary carcinomas, are multifocal and multicentric. Thyroidectomy is not required in thyroglossal cyst carcinomas of nonthyroid origin. We report two cases of thyroglossal cyst with incidental finding of papillary carcinoma of thyroid origin due to their rarity with a review of literature.
ISSN:2347-8128
2347-8128